Critical Incidents and Safety of Xenon Anesthesia in Abdominal Surgery

A.Yu. Kulikov1, O.V. Kuleshov1, 2, K.M. Lebedinskiy2

1 Saint-Petersburg Multiprofile Сenter, Saint-Petersburg

2 Ilya I. Mechinkov North-Western State Medical University, Saint-Petersburg

For correspondence: Kulikov Alexey Yurievich — anaesthetist, Saint-Petersburg,; e-mail:

For citation: Kulikov AYu, Kuleshov OV, Lebedinskiy KM. Critical Incidents and Safety of Xenon Anesthesia in Abdominal Surgery. Intensive Care Herald. 2016;3:22–26.

Xenon is the most promising anesthetic of the XXI century, in many ways close to the ideal. The aim of this study was to investigate the safety of the balanced general and combined xenon anesthesia by analysis of intraoperative critical incidents (CI). A retrospective data analysis of anesthesia with extended hemodynamic monitoring in 80 patients, underwent elective abdominal surgery, was done. Depending on the anesthesia’s type and basic inhalation agent (xenon or sevoflurane), patients were divided into 3 groups. The structure and frequency of intraoperative CI was observed. Under balanced general and combined xenon anesthesia main hemodynamic incidents were decrease in cardiac output and bradycardia, while in the sevoflurane group decrease of cardiac output and hypotension prevailed. The frequency of other CI did not differ significantly. Xenon anesthesia is safe and effective in patients undergoing abdominal surgery.

Keywords: xenon, sevoflurane, general anesthesia, critical incident, safety

Received: 09.08.2016


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