Xenon anesthesia during the oral cavity sanitation in child with consequences of perinatal brain damage (case report)

V.V. Lazarev1, D.M. Haliullin2, R.R. Gabdrafikov2, E.S. Gracheva2, E.E. Kuznetsova3, D.V. Koshcheev2

1 «Pirogov Russian National Research Medical University», Moscow

2 LLC “Dental Forte Elit”, Naberezhnye Chelny

3 PAHI “Municipal Hospital No. 5’, Naberezhnye Chelny

For correspondence: Dinar M. Haliullin, doctor intensivist of LLC Dental Forte Elit, Naberezhnye Chelny; e-mail: dr170489@yandex.ru

For citation: Lazarev VV, Haliullin DM, Gabdrafikov RR, Gracheva ES, Kuznetsova EE, Koshcheev DV. Xenon anesthesia during the oral cavity sanitation in child with consequences of perinatal brain damage (case report). Alexander Saltanov Intensive Care Herald. 2019;2:105–110.

DOI: 10.21320/1818-474X-2019-2-105-110


Halogenated inhalation anesthetics have some adverse effects, including the ability to have a negative effect on the developing brain in children, one of the manifestations of which are cognitive dysfunctions, especially in the younger age group. The article presents a clinical case of xenon in combined inhalation anesthesia in a child with the consequences of perinatal brain damage. During anesthesia, a spontaneous ventilation mode was applied with pressure support ventilation (PSV). There was noted high efficacy and safety xenon anesthesia in a dental treatment, the absence of the effect of anesthesia on cognitive function in a child with a compromised nervous system. It is advisable to further study the use of xenon in the pediatric dentistry anesthesia.

Keywords: xenon, inhalation anesthesia, volatile anesthetics, children, dentistry

Received: 27.01.2019


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Syndrome of Postnarcosis Excitation and its Prophylaxis in Anesthesia with Sevoflurane in Pediatric Oncology

S.V. Tumanyan, E.Yu. Semiletkina, D.A. Rozenko

Rostov Research Oncology Institute, Russian Federation Ministry of Healthcare of the Russian Federation, Rostov-on-Don

For correspondence: Tumanyan Sergey Vartanovich — MD, professor, head of the Department of Anesthesiology and Reanimatology of the Rostov Research Oncology Institute, Federal Ministry of Health, Rostov-on-Don; e-mail: stv53@mail.ru

For citation: Tumanyan SV, Semiletkina EYu, Rozenko DA. Syndrome of Postnarcosis Excitation and Its Prophylaxis in Anesthesia with Sevoflurane in Pediatric Oncology. Intensive Care Herald. 2017;2:31–36.


Sevoflurane is the «gold standard» in pediatric anesthesia, because Does not irritate the upper respiratory tract, has a cardioprotec- tive effect, is easily controlled. Along with this, sevoflurane also has side effects, of which the most interesting is the syndrome of post- narcotic excitement, expressed by expressed anxiety, motor excitement, negativism. For its prevention, dexmedetomidine can be used. The goal is to select the optimal method of prevention of post-nasal exacerbation syndrome (SPNV) in young children with oncological pathology with sevoflurane inhalation anesthesia. Materials and methods. 90 children with oncological pathology aged from 1 year to 4 years, body weight from 9 to 18 kg, physical status according to ASA II–III were examined. Depending on the method of prevention of SPNV, children were divided into three groups: 1st group of children who had undergone sevoflurane inhalation anesthesia; 2nd group of children who, after anesthesia with sevoflurane, received propofol, 3rd group — children who, prior to anesthesia with sevoflurane, intranasally injected dexmedetomidine. Conclusions. Administration of propofol at the end of inhalation with sevoflurane prevents the development of SPNV in children in 82.8% of cases, prolongs the phase of medicamentous sedation, reduces hypersympathicoto- nia. Short-term depression of respiration in response to the administration of propofol requires 100 % oxygen inhalation. Intranasal administration of dexmedetomidine 30 minutes prior to the onset of anesthesia prevents the development of SPNV in children after inhalation anesthesia with sevoflurane in 90% of cases.

Keywords: postnarcosis excitation syndrome, children, dexmedetomidine, sevoflurane, oncology

Received: 10.03.2017


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Clinical Parallels of the Tactics of Volemic Resuscitation and Nutritional Support with the Outcomes of Severe Thermal Burns in Children

K.S. Botvina, N.P. Pyshmintseva, N.P. Shen, Yu.Kh. Sayfitdinov, D.V. Suchkov

Department of anesthesiology and resuscitation of the Institute of continuous professional development Tyumen state medical university Ministry of Healthcare Russian Federation; Provincial clinical hospital № 1, Tyumen

For correspondence: Natalia Petrovna Shen — M.D., professor, chairman of department of anesthesiology and resuscitation of the institute of continuous professional development Tyumen GMU of the Ministry of Pub. Health of Russia, Tyumen; e-mail: nataliashen@rambler.ru

For citation: Botvina KS, Pyshmintseva NP, Shen NP, Sayfitdinov YuKh, Suchkov DV. Clinical Parallels of the Tactics of Volemic Resuscitation and Nutritional Support with the Outcomes of Severe Thermal Burns in Children. Intensive Care Herald. 2017;2:17–20.


In the article are studied the demographic, tactical and prognostic aspects of burn disease in children for the purpose of the devel- opment of the important clinical parallels, including of the mechanisms, which start the multiple organ system dysfunction, infectious complications and death. The results of a study showed that prevalence and the depth of defeat does not be determining for the possi- bility to master nourishment and it must not become the factor, which impedes the beginning of nutritional support within maximally early periods. The authors also established that the positive fluid balance administered for the first three days of ICU in children with the severe burns is not the predictor of complications or lethal outcome, which separates this population of patients from the number of majority of the patients, in whom the so-called Fluid overload is the independent factor of the risk of complications and lethal outcome.

Keywords: burn, children, severe thermal burns

Received: 08.03.2017


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