Change of the temperature balance of the brain in various types of general anesthesia

A.V. Butrov, K.A. Salimova, B.J. Torosyan, G.R. Makhmutova, P.P. Davydov

Peoplesʼ Friendship University of Russia, Moscow

For correspondence: Salimova Kamila Azatovna — resident Peoplesʼ Friendship University of Russia, Moscow, Moscow; e-mail:

For citation: Butrov AV, Salimova KA, Torosyan BJ, Makhmutova GR, Davydov PP. Change of the temperature balance of the brain in various types of general anesthesia. Alexander Saltanov Intensive Care Herald. 2018;3:72–6.

DOI: 10.21320/1818-474X-2018-3-72-76

Under the influence of general anesthesia various functions of the body can change depending on the main and concomitant diseases, the type and volume of the surgical intervention. General anesthesia is traditionally associated with the loss of normal thermoregulatory mechanisms. The intracranial temperature of 32 patients were measured in this study. These patients were divided into 3 groups depending on the type of general anesthesia. The brain temperature of all patients were measured by recording the strength of the electromagnetic radiation from deep brain tissues and also, the axillary and tympanic temperatures were measured. According to the thermometry results of the brain, it was evident that when using Propofol, the temperature of the brain during anesthesia decreased by 1.21 ± 0.19 °C. During the maintenance of inhalational anesthesia the temperature of the brain decreased by 0.69 ± 0.15 °C. There was a decrease of brain temperature in all patients from all 3 groups and the temperature gradient of the brain/axillary region increased. Therefore, we concluded that the decrease in brain temperature occurs not only because of thermoregulatory center temperature decrease, but also because of reduced brain metabolism and/or cerebral blood flow. Propofol in a greater degree causes brain temperature decrease which may be important for the prevention or treatment of conditions that are accompanied by an increase in brain temperature or perfusion-metabolic balance disturbances (for example in neuroanesthesiology and in operations on the main cerebral vessels).

Keywords: brain temperature, temperature balance, microwave thermometry, propofol, sevoflurane, general anesthesia

Received: 02.04.2018


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Morphine Epidural Analgesia in Spine Deformity Surgery

K.Yu. Ukolov, V.L. Aizenberg, N.I. Arzhakova

FGBU «CITO named after N.N. Priorov» of Ministry of Health of Russian Federation, Moscow

For correspondence: Ukolov Konstantin Iurievich — Candidate of Science, Central Institute of Traumatology and Orthopedics named after N.N. Priorov of the Russian Ministry of Health, Moscow; e-mail:

For citation: Ukolov KYu, Aizenberg VL, Arzhakova NI. Morphine Epidural Analgesia in Spine Deformity Surgery. Intensive Care Herald. 2017;1:32–36.

Introduced comparative analysis of two methods of anesthesia during surgery dorsal correction of the spine deformity in 123 patients. The quality of analgesia was assessed using hemodynamic parameters, biochemistry markers of stress, blood loss value and frequency of early postoperative complications. Total 42 patient underwent surgery under general anesthesia with mechanical ventilation, using sevoflurane and fentanyl. In 81 patients used general anesthesia, combined with epidural analgesia using 15 morphine (100 mcg/kg in 10–12 ml of saline). Use of morphine epidural analgesia in addition to general anesthesia increase quality of nociception defence, significantly decrease consumption of narcotic analgesics, anesthetics and relaxants, decrease blood loss by 10 % and frequency of complications by 20 %.

Keywords: spine deformity, scoliosis surgery, dorsal correction, general anesthesia, morphine general anesthesia

Received: 24.22.2017


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Critical Incidents and Safety of Xenon Anesthesia in Abdominal Surgery

A.Yu. Kulikov1, O.V. Kuleshov1, 2, K.M. Lebedinskiy2

1 Saint-Petersburg Multiprofile Сenter, Saint-Petersburg

2 Ilya I. Mechinkov North-Western State Medical University, Saint-Petersburg

For correspondence: Kulikov Alexey Yurievich — anaesthetist, Saint-Petersburg,; e-mail:

For citation: Kulikov AYu, Kuleshov OV, Lebedinskiy KM. Critical Incidents and Safety of Xenon Anesthesia in Abdominal Surgery. Intensive Care Herald. 2016;3:22–26.

Xenon is the most promising anesthetic of the XXI century, in many ways close to the ideal. The aim of this study was to investigate the safety of the balanced general and combined xenon anesthesia by analysis of intraoperative critical incidents (CI). A retrospective data analysis of anesthesia with extended hemodynamic monitoring in 80 patients, underwent elective abdominal surgery, was done. Depending on the anesthesia’s type and basic inhalation agent (xenon or sevoflurane), patients were divided into 3 groups. The structure and frequency of intraoperative CI was observed. Under balanced general and combined xenon anesthesia main hemodynamic incidents were decrease in cardiac output and bradycardia, while in the sevoflurane group decrease of cardiac output and hypotension prevailed. The frequency of other CI did not differ significantly. Xenon anesthesia is safe and effective in patients undergoing abdominal surgery.

Keywords: xenon, sevoflurane, general anesthesia, critical incident, safety

Received: 09.08.2016


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Level of consciousness evaluation during anesthesia in pediatric patients (review)

L.E. Tsypin, A.A. Ovchinnikova

GBOY VPO “RNIMU named after N.I. Pirogov” Ministry of Health of Russia, Moscow

For citation: Tsypin LE, Ovchinnikova AA. Level of consciousness evaluation during anesthesia in pediatric patients (review). Intensive Care Herald. 2016;1:12–16.

The review is based on the data from PudMed, Scopus, Medline, peer-reviewed medical journals, guidelines and clinical manuals. Up-to-date and previous clinical practice, technology, equipment and methods of assessing the level of consciousness during anesthesia in children are discussed. Particular attention is paid to the reliability of the data and the age limits of discussed techniques.

Keywords: general anesthesia, entropy, BIS-index, level of consciousness, pediatric patients.


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