Monitoring of Muscle Relaxation in Routine Anesthesia Practice: Three-year Experience

S.V. Chuprin1, O.V. Sushkova1, L.N. Girinskaia1, S.A. Kuznetsov1, V.V. Myasnikova2

1 Base Obstetrics and Gynecology Clinic of Kuban State Medical University, Ministry of Healthcare of the Russian Federation, Krasnodar

2 FSАI S.N. Fyodorov IRTC «Eye Microsurgery» of the Ministry of Healthcare of the Russian Federation, Krasnodar

For correspondence: Chuprin Sergey Vyacheslavovich — Candidate of Science, Head of the Department of anesthesiology and intensive care, Base Obstetrics and Gynecology Clinic of Kuban State Medical University, Ministry of Healthcare of the Russian Federation, Krasnodar; e-mail:

For citation: Chuprin SV, Sushkova OV, Girinskaia LN, Kuznetsov SA, Myasnikova VV. Monitoring of Muscle Relaxation in Routine Anesthesia Practice: Three-year Experience. Intensive Care Herald. 2017;1:23–27.

Neuromuscular block is a really significant component of anesthesia during surgery operations. At this time, individual sensitivity to neuromuscular blocking differs considerably and depends on great number of factors. The main task of conduct of neuromuscular monitoring is exclusion of residual block and recovery of neuromuscular conductivity. We present analysis of three years’ experience of application of monitoring of neuromuscular conductivity. The aim of the research is the estimation of effectiveness of usage of monitoring of neuromuscular conductivity in daily practice of anesthesia service for provision of patients’ security and formation of comfortable conditions for surgeons’ work. Materials and methods. In our research, we included 4459 patients who had operating treatment under general anesthesia. All the patients were divided in two groups. In the first group (2355 patients) during anesthesia there used monitor TOF-Watch SX (Organon, Ireland). In the second group (2104 patients) monitoring of neuromuscular conductivity was not performed. Results. The received results lead to the conclusion that application of monitoring of neuromuscular conductivity allowed to decrease statistically number of incidents connected with insufficient neuromuscular blocking or impaired reversion of neuromuscular block. Absence of statistically considerable differences in quantity of hyperdynamic reactions in the circulatory system connected with intubation, probably, is caused by great quantity of heterogeneous factors of influence on this index. Also, application of monitor of neuromuscular conductivity made it possible to conform to a surgeon’s expectations, ensuring muscular relaxation suitable for surgery conditions. Conclusion. Usage of monitors of neuromuscular conductivity in routine anesthesia practice is necessary and essential for ensuring patients’ security and creation of comfortable conditions for surgeons work.

Keywords: muscle relaxants, neuromuscular block, neuromuscular monitoring, TOF-mode, reversion

Received: 24.12.2016


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To the question about factors influencing neuromuscular blockade

G.G. Bestaev, V.D. Slepushkin

North-Ossetian State Medical Academy, Vladikavkaz

For correspondence: Georgy Bestaev — assistant of Department of anesthesiology and critical care medicine of North-Ossetian State Medical Academy; e-mail:

For citation: Bestaev GG, Slepushkin VD. To the question about factors influencing neuromuscular blockade. Alexander Saltanov Intensive Care Herald. 2018;2:36–9.

DOI: 10.21320/1818-474X-2018-2-36-39

It has long been known that the duration of the action of muscle relaxants is affected by a variety of factors, and to a greater extent this effect is observed when using non-depolarizing muscle relaxants of medium and long duration. Surprisingly, factors, influencing neuromuscular block, are not becoming the subject of scientific discussion and are not reflected in modern literature. It is absolutely obvious at the same time that the study of quantitative dynamics of neuromuscular block represents a significant scientific and practical interest. In the given literature review the most important factors will be considered and discussed.

Keywords: factors, muscle relaxants, neuromuscular block, inhalational anesthetics, smoking, electrolytes, temperature, circadian rhythm

Received: 07.02.2018


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