Critical Incidents and Safety of Xenon Anesthesia in Abdominal Surgery

A.Yu. Kulikov1, O.V. Kuleshov1, 2, K.M. Lebedinskiy2

1 Saint-Petersburg Multiprofile Сenter, Saint-Petersburg

2 Ilya I. Mechinkov North-Western State Medical University, Saint-Petersburg

For correspondence: Kulikov Alexey Yurievich — anaesthetist, Saint-Petersburg,; e-mail: alexeykulikov1987@yandex.ru

For citation: Kulikov AYu, Kuleshov OV, Lebedinskiy KM. Critical Incidents and Safety of Xenon Anesthesia in Abdominal Surgery. Intensive Care Herald. 2016;3:22–26.


Xenon is the most promising anesthetic of the XXI century, in many ways close to the ideal. The aim of this study was to investigate the safety of the balanced general and combined xenon anesthesia by analysis of intraoperative critical incidents (CI). A retrospective data analysis of anesthesia with extended hemodynamic monitoring in 80 patients, underwent elective abdominal surgery, was done. Depending on the anesthesia’s type and basic inhalation agent (xenon or sevoflurane), patients were divided into 3 groups. The structure and frequency of intraoperative CI was observed. Under balanced general and combined xenon anesthesia main hemodynamic incidents were decrease in cardiac output and bradycardia, while in the sevoflurane group decrease of cardiac output and hypotension prevailed. The frequency of other CI did not differ significantly. Xenon anesthesia is safe and effective in patients undergoing abdominal surgery.

Keywords: xenon, sevoflurane, general anesthesia, critical incident, safety

Received: 09.08.2016


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Efficacy and safety sevoflurane during microsurgical operations conceringe brain aneurysm

S.V. Tsilina2,1, N.V. Govorova1, V.N. Lukach1, V.K. Polomoshnov2, Y.A. Shesterikov2

1State budget institution of higher professional education «Omsk State Medical Academy», Ministry for health care, Omsk

2Official health agency «City Clinical Emergency Hospital №1», Omsk

For citation: Tsilina SV, Govorova NV, Lukach VN et al. Efficacy and safety of sevoflurane during brain aneurysm microsurgeries. Intensive Care Herald. 2016;1:32–35.


The analysis of the efficacy and safety of sevoflurane during microsurgical interventions for aneurysms of the brain in 20 patients. Patients were divided into 2 groups according to the severity of subarachnoid hemorrhage scale Hunt-Hess and relaxation techniques used by the brain. Analyzed the postoperative period, and outcomes of patients according to the Glasgow outcome scale. Sevoflurane by the method of low-flow anesthesia provided good handling, maintaining an adequate level of anesthesia for a long surgery, enables wake and evaluation of neurological status in the early postoperative period. Application of sevoflurane during anesthesia in patients with mikrohiruricheskih interventions for cerebral aneurysms is feasible and safe, perioperative proceeds more favorably with the severity of hemorrhage I-II class at Hunt-Hess.

Keywords: microneurosurgical operation, sevoflurane, efficiency, safety, Hunt-Hess scale.


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