Change of the temperature balance of the brain in various types of general anesthesia

A.V. Butrov, K.A. Salimova, B.J. Torosyan, G.R. Makhmutova, P.P. Davydov

Peoplesʼ Friendship University of Russia, Moscow

For correspondence: Salimova Kamila Azatovna — resident Peoplesʼ Friendship University of Russia, Moscow, Moscow; e-mail:

For citation: Butrov AV, Salimova KA, Torosyan BJ, Makhmutova GR, Davydov PP. Change of the temperature balance of the brain in various types of general anesthesia. Alexander Saltanov Intensive Care Herald. 2018;3:72–6.

DOI: 10.21320/1818-474X-2018-3-72-76

Under the influence of general anesthesia various functions of the body can change depending on the main and concomitant diseases, the type and volume of the surgical intervention. General anesthesia is traditionally associated with the loss of normal thermoregulatory mechanisms. The intracranial temperature of 32 patients were measured in this study. These patients were divided into 3 groups depending on the type of general anesthesia. The brain temperature of all patients were measured by recording the strength of the electromagnetic radiation from deep brain tissues and also, the axillary and tympanic temperatures were measured. According to the thermometry results of the brain, it was evident that when using Propofol, the temperature of the brain during anesthesia decreased by 1.21 ± 0.19 °C. During the maintenance of inhalational anesthesia the temperature of the brain decreased by 0.69 ± 0.15 °C. There was a decrease of brain temperature in all patients from all 3 groups and the temperature gradient of the brain/axillary region increased. Therefore, we concluded that the decrease in brain temperature occurs not only because of thermoregulatory center temperature decrease, but also because of reduced brain metabolism and/or cerebral blood flow. Propofol in a greater degree causes brain temperature decrease which may be important for the prevention or treatment of conditions that are accompanied by an increase in brain temperature or perfusion-metabolic balance disturbances (for example in neuroanesthesiology and in operations on the main cerebral vessels).

Keywords: brain temperature, temperature balance, microwave thermometry, propofol, sevoflurane, general anesthesia

Received: 02.04.2018


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Syndrome of Postnarcosis Excitation and its Prophylaxis in Anesthesia with Sevoflurane in Pediatric Oncology

S.V. Tumanyan, E.Yu. Semiletkina, D.A. Rozenko

Rostov Research Oncology Institute, Russian Federation Ministry of Healthcare of the Russian Federation, Rostov-on-Don

For correspondence: Tumanyan Sergey Vartanovich — MD, professor, head of the Department of Anesthesiology and Reanimatology of the Rostov Research Oncology Institute, Federal Ministry of Health, Rostov-on-Don; e-mail:

For citation: Tumanyan SV, Semiletkina EYu, Rozenko DA. Syndrome of Postnarcosis Excitation and Its Prophylaxis in Anesthesia with Sevoflurane in Pediatric Oncology. Intensive Care Herald. 2017;2:31–36.

Sevoflurane is the «gold standard» in pediatric anesthesia, because Does not irritate the upper respiratory tract, has a cardioprotec- tive effect, is easily controlled. Along with this, sevoflurane also has side effects, of which the most interesting is the syndrome of post- narcotic excitement, expressed by expressed anxiety, motor excitement, negativism. For its prevention, dexmedetomidine can be used. The goal is to select the optimal method of prevention of post-nasal exacerbation syndrome (SPNV) in young children with oncological pathology with sevoflurane inhalation anesthesia. Materials and methods. 90 children with oncological pathology aged from 1 year to 4 years, body weight from 9 to 18 kg, physical status according to ASA II–III were examined. Depending on the method of prevention of SPNV, children were divided into three groups: 1st group of children who had undergone sevoflurane inhalation anesthesia; 2nd group of children who, after anesthesia with sevoflurane, received propofol, 3rd group — children who, prior to anesthesia with sevoflurane, intranasally injected dexmedetomidine. Conclusions. Administration of propofol at the end of inhalation with sevoflurane prevents the development of SPNV in children in 82.8% of cases, prolongs the phase of medicamentous sedation, reduces hypersympathicoto- nia. Short-term depression of respiration in response to the administration of propofol requires 100 % oxygen inhalation. Intranasal administration of dexmedetomidine 30 minutes prior to the onset of anesthesia prevents the development of SPNV in children after inhalation anesthesia with sevoflurane in 90% of cases.

Keywords: postnarcosis excitation syndrome, children, dexmedetomidine, sevoflurane, oncology

Received: 10.03.2017


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Parameters of External Ventilation in Performing Endoscopic Operations Using Low-flow Inhalational Anesthesia with Preservation of Spontaneous Ventilation via Epiglottic Airduct «i-gel»

A.I. Gritsan1, M.V. Krotov1, R.A. Bichurin2

1Krasnoyarsk state medical University named after V.F. Voyno-Yasenetsky, Krasnoyarsk

2Krasnoyarsk Interdistrict clinical hospital № 4, Krasnoyarsk

For correspondence: Alexey I. Gritsan — MD, Professor, head of Department of anesthesiology and critical care medicine of Krasnoyarsk state medical University named after V.F. Voyno-Yasenetsky; e-mail:

For citation: Gritsan AI, Krotov MV, Bichurin RA. Parameters of External Ventilation in Performing Endoscopic Operations Using Low-fl ow Inhalational Anesthesia with Preservation of Spontaneous Ventilation via Epiglottic Airduct «i-gel». Intensive Care Herald. 2016;3:27–31.

The aim of the study was a comparative study of the status and changes of parameters of external respiration at carrying out of endoscopic surgery for tubal infertility using low-flow sevoflurane- or desflurane-based anesthesia, the application of epiglottis duct I-gel and the mode of ventilation with pressure support (PS). Investigated 100 patients with tubal infertility, which produced surgical treatment of infertility under General sevoflurane- or desflurane-based anaesthesia, using epiglottis duct and the use of ventilation with pressure support (PS). The study results showed that when conducting low-flow sevoflurane- or desflurane-based anesthesia with maintained spontaneous breathing through the epiglottis duct, the changes of parameters of the biomechanics of respiration in both groups are of unidirectional character and the highest values of deviation from the source parameters at the third stage of the research (15 minutes after the imposition of carboxyperitoneum), however, do not affect the gas exchange that shows the safety of these methods of anesthesia and the possibility of their application in everyday clinical practice.

Keywords: sevoflurane, desflurane, low-flow anaesthesia, epiglottis airduct, infertility

Received: 02.06.2016


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Critical Incidents and Safety of Xenon Anesthesia in Abdominal Surgery

A.Yu. Kulikov1, O.V. Kuleshov1, 2, K.M. Lebedinskiy2

1 Saint-Petersburg Multiprofile Сenter, Saint-Petersburg

2 Ilya I. Mechinkov North-Western State Medical University, Saint-Petersburg

For correspondence: Kulikov Alexey Yurievich — anaesthetist, Saint-Petersburg,; e-mail:

For citation: Kulikov AYu, Kuleshov OV, Lebedinskiy KM. Critical Incidents and Safety of Xenon Anesthesia in Abdominal Surgery. Intensive Care Herald. 2016;3:22–26.

Xenon is the most promising anesthetic of the XXI century, in many ways close to the ideal. The aim of this study was to investigate the safety of the balanced general and combined xenon anesthesia by analysis of intraoperative critical incidents (CI). A retrospective data analysis of anesthesia with extended hemodynamic monitoring in 80 patients, underwent elective abdominal surgery, was done. Depending on the anesthesia’s type and basic inhalation agent (xenon or sevoflurane), patients were divided into 3 groups. The structure and frequency of intraoperative CI was observed. Under balanced general and combined xenon anesthesia main hemodynamic incidents were decrease in cardiac output and bradycardia, while in the sevoflurane group decrease of cardiac output and hypotension prevailed. The frequency of other CI did not differ significantly. Xenon anesthesia is safe and effective in patients undergoing abdominal surgery.

Keywords: xenon, sevoflurane, general anesthesia, critical incident, safety

Received: 09.08.2016


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Efficacy and safety sevoflurane during microsurgical operations conceringe brain aneurysm

S.V. Tsilina2,1, N.V. Govorova1, V.N. Lukach1, V.K. Polomoshnov2, Y.A. Shesterikov2

1State budget institution of higher professional education «Omsk State Medical Academy», Ministry for health care, Omsk

2Official health agency «City Clinical Emergency Hospital №1», Omsk

For citation: Tsilina SV, Govorova NV, Lukach VN et al. Efficacy and safety of sevoflurane during brain aneurysm microsurgeries. Intensive Care Herald. 2016;1:32–35.

The analysis of the efficacy and safety of sevoflurane during microsurgical interventions for aneurysms of the brain in 20 patients. Patients were divided into 2 groups according to the severity of subarachnoid hemorrhage scale Hunt-Hess and relaxation techniques used by the brain. Analyzed the postoperative period, and outcomes of patients according to the Glasgow outcome scale. Sevoflurane by the method of low-flow anesthesia provided good handling, maintaining an adequate level of anesthesia for a long surgery, enables wake and evaluation of neurological status in the early postoperative period. Application of sevoflurane during anesthesia in patients with mikrohiruricheskih interventions for cerebral aneurysms is feasible and safe, perioperative proceeds more favorably with the severity of hemorrhage I-II class at Hunt-Hess.

Keywords: microneurosurgical operation, sevoflurane, efficiency, safety, Hunt-Hess scale.


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