Dynamics of cognitive functions in the early postoperative period after spinal neurosurgical operations


A.V. Solenkova, A.A. Poddubskaya, A.Yu.Lubnin, D.A. Moshchev, N.A. Dzyubanova

“National Medical Research Center of Neurosurgery” named after N.N. Burdenko Ministry of Health of Russian Federation, Moscow

For correspondence: Lubnin Andrei Yurevich — MD, Professor, head of Department of anaesthesiology and intensive care unit “National Medical Research Center of Neurosurgery” named after Ac. N.N. Burdenko Ministry of Health of Russian Federation, Moscow; e-mail: lubnin@nsi.ru

For citation: Solenkova AV, Poddubskaya AA, Lubnin AYu, et al. Dynamics of Cognitive Functions in the Early Postoperative Period after Spinal Neurosurgical Operations. Alexander Saltanov Intensive Care Herald. 2018;1:27–36.

DOI: 10.21320/1818-474X-2018-1-27-36

The aim of the study was to study cognitive changes in the early postoperative period after spinal neurosurgical operations. Material and methods. 80 patients were operated with spinal pathology. The patients were divided into two groups: the 1st group consisted of 40 patients under the age of 60 (mean age 42 ± 11.6), the second group consisted of 40 patients aged 60 years and older (mean age was 68 ± 9.77). Various methods of anesthesia were used in the work. Neuropsychological examination in accordance with the general clinical protocol before the operation and 5–7 days after the operation. The following factors for evaluation were chosen: duration of anesthesia, hemodynamics, anesthesia method and type of anesthetic, monitoring of the depth of anesthesia using BIS technology. Results. Patients ≥ 60 years before the operation had cognitive changes in working memory and regulatory functions aggravated in the postoperative period. With short anesthesia (< 200 minutes), significant differences in test results before and after surgery were not obtained. Prolonged anesthesia (≥ 200 minutes) has negative effects on cognitive functions based on the results of the working memory test and MOCA. A greater decrease in neurodynamic parameters and MOCA scores is observed with the intravenous propofol anesthesia compared with an inhaled anesthesia with sevoflurane.

Keywords: cognitive functions, spinal pathology, spinal operations, postoperative cognitive dysfunction

Received: 20.12.2017

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