Morphine Epidural Analgesia in Spine Deformity Surgery


K.Yu. Ukolov , V.L. Aizenberg , N.I. Arzhakova

Central Institute of Traumatology and Orthopedics named after N.N. Priorov, Moscow, Russia

For correspondence: Konstantin Yu. Ukolov— Candidate of Science, Central Institute of Traumatology and Orthopedics named after N.N. Priorov, Moscow; e-mail:

For citation: Ukolov K.Yu., Aizenberg V.L., Arzhakova N.I. Morphine epidural analgesia in spine deformity surgery. Intensive Care Herald. 2017;1:33–37. DOI: 10.21320/1818-474X-2017-1-33-37

Objective. Introduced comparative analysis of two methods of anesthesia during surgery dorsal correction of the spine deformity. Material and Methods. The quality of analgesia was assessed in 123 patients using hemodynamic parameters, biochemistry markers of stress, blood loss value and frequency of early postoperative complications. Total 42 patient underwent surgery under general anesthesia with mechanical ventilation, using sevoflurane and fentanyl. In 81 patients used general anesthesia, combined with epidural analgesia using 15 morphine (100 mcg/kg in 10–12 ml of saline). Results. Use of morphine epidural analgesia in addition to general anesthesia increase quality of nociception defence, significantly decrease consumption of narcotic analgesics, anesthetics and relaxants, decrease blood loss by 10 % and frequency of complications by 20 %.

Keywords: spine deformity, scoliosis surgery, dorsal correction, general anesthesia, morphine general anesthesia

Received: 24.22.2017

Read in PDF


  1. Айзенберг В.Л., Уколов К.Ю., Диордиев А.В. Методы анестезии при оперативном лечении сколиоза у детей. Анестезиология и реаниматология. 2010; 1: 57–60. [Aizenberg V.L., Ukolov K.Yu., Diordiev A.V. Methods of anesthesia during surgical treatment for scoliosis in children. Anest. i reanim. 2010; 1: 57–60. (In Russ)]
  2. Айзенберг В.Л., Ульрих Г.Э., Цыпин Л.Е., Заболотский Д.В. Регионарная анестезия в педиатрии: Монография. СПб.: Синтез Бук, 2011. [Aizenberg V.L., Ulrih G.E., Tsypin L.E, Zabolotskii D.V. Regionarnaya anesteziya v pediatrii: Monograph. Saint Petersburg: Sintez Book, (In Russ)]
  3. Анестезия в педиатрии: Пер. с англ. Под ред. Дж.А. Грегори. М.: Медицина, 2003: 797–832. [Anesteziya v pediatrii: Transl. from En. Ed.: J.A. Gregory. Moscow: Medicine, 2003. (In Russ)]
  4. Лебедева М.Н. Анестезиологическое обеспечение одномоментной двухэтапной хирургической коррекции сколиоза: Автореф. дис. … канд. мед. наук. Новосибирск, 2001. [Lebedeva M.N. Anesteziologicheskoe obespechenie odnomomentnoi dvuhetapnoi hirurgicheskoi korrektsii skolioza: Avtoref. dis. … kand. med. nauk. Novosibirsk, 2001. (In Russ)]
  5. Behar M., Magora F., Davidson S.T. Epidural morphine in treatment of pain. Lancet. 1979; 1(8): 527–528. doi: 10.1016/S0140-6736(79)90947-4.
  6. Ravish M., Muldowney B., Becker A. et al. Pain management in patients with adolescent idiopathic scoliosis undergoing posterior spinal fusion: combined intrathecal morphineand continuous epidural versus PCA. J. Pediatr. Orthop. 2012; 32: 799–804. doi: 10.1097/BPO.0b013e3182694f00.
  7. Tobias J.D. A review of intrathecal and epidural analgesia after spinal surgery in children. Anesth. Analg. 2004; 98(4): 956–965 doi: 10.1213/01.ANE.0000107938.80562.75.
  8. Wiggins G.C., Shaffrey C.I., Abel M.F., Menezes A.N. Pediatric spinal deformations. Neurosurg. Focus. 2003; 15: 14–15. doi: 10.3171/foc.2003.14.1.4.