Remaxol dose-dependent effect on central hemodynamics and metabolism in generalized peritonitis


Yu.P. Orlov, V.N. Lukacs, N.V. Govorova, A.V. Glushchenko, O.D. Dmitrieva

GBOY VPO “Omsk State Medical University” Ministry of Health of Russia, Omsk

For citation: Orlov YuP, Lukach VN, Govorova NV et al. Remaxol dose-dependent effect on central hemodynamics and metabolism in generalized peritonitis. Intensive Care Herald. 2016;1:27–32.

The aim of the study was to investigate the effectiveness of inclusion in remaxol regimens on hemodynamic parameters and processes of cellular metabolism in patients with severe generalized peritonitis.

Results of treatment of 24 patients who received preoperative medication preparation and surgical treatment in accordance with the standards of conduct, in the postoperative period 2 groups with the same intensive treatment protocol were formed. Patients of the first group (n=12) were administered for 5 days remaxol 800 ml per day. The second group (control) (n=12) in the program which remaxol infusion therapy was not used.

Results of the study showed that the inclusion of infusion therapy remaxol scheme in the postoperative period in patients with generalized peritonitis ensures efficient utilization of glucose and oxygen, reduces the severity of oxygen debt at the tissue level, providing mechanisms of oxidation on the more familiar processes for fabrics way, providing at the same time kateholaminomimetichesky effect, providing an earlier period when the central and stabilization of hemodynamic parameters during its injection velocity of 30 to 60 ml per hour.

Keywords: generalized peritonitis, remaxol, infusion therapy, lactate.


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