ISSN (print) 1726-9806     ISSN (online) 1818-474X
No. 2 (2017), ANESTHESIOLOGY
No. 2 (2017)
ANESTHESIOLOGY

Syndrome of Postnarcosis Excitation and its Prophylaxis in Anesthesia with Sevoflurane in Pediatric Oncology

Published 24.06.2017
Sergey V. Tumanyan
Rostov State Research Institute of Oncology, Rostov-on-Don, Russia
https://orcid.org/0000-0002-1411-0433
E.Yu. Semiletkina
Rostov State Research Institute of Oncology, Rostov-on-Don, Russia
https://orcid.org/0000-0002-4850-0421
D.A. Rozenko
Rostov State Research Institute of Oncology, Rostov-on-Don, Russia
https://orcid.org/0000-0002-5563-484X
#2017-2
PDF_2017-2_31-36 (Russian)

Keywords

postnarcosis excitation syndrome
children
dexmedetomidine
sevoflurane
oncology

How to Cite

1.
Tumanyan S.V., Semiletkina E.Y., Rozenko D.A. Syndrome of Postnarcosis Excitation and its Prophylaxis in Anesthesia with Sevoflurane in Pediatric Oncology. Annals of Critical Care. 2017;(2):31-36. doi:10.21320/1818-474X-2017-2-31-36
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Abstract

Introduction. Sevoflurane is the «gold standard» in pediatric anesthesia, because Does not irritate the upper respiratory tract, has a cardioprotec- tive effect, is easily controlled. Along with this, sevoflurane also has side effects, of which the most interesting is the syndrome of post- narcotic excitement, expressed by expressed anxiety, motor excitement, negativism. For its prevention, dexmedetomidine can be used. Objectives: is to select the optimal method of prevention of post-nasal exacerbation syndrome (SPNV) in young children with oncological pathology with sevoflurane inhalation anesthesia. Materials and methods. 90 children with oncological pathology aged from 1 year to 4 years, body weight from 9 to 18 kg, physical status according to ASA II–III were examined. Depending on the method of prevention of SPNV, children were divided into three groups: 1st group of children who had undergone sevoflurane inhalation anesthesia; 2nd group of children who received propofol, after anesthesia with sevoflurane; 3rd group — children with intranasally injected dexmedetomidine, prior to anesthesia with sevoflurane. Results. Administration of propofol at the end of inhalation with sevoflurane prevents the development of SPNV in children in 82.8% of cases, prolongs the phase of medicamentous sedation, reduces hypersympathicoto- nia. Short-term depression of respiration in response to the administration of propofol requires 100 % oxygen inhalation. Conclusion. Intranasal administration of dexmedetomidine 30 minutes prior to the onset of anesthesia prevents the development of SPNV in children after inhalation anesthesia with sevoflurane in 90% of cases.

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