Периоперационная респираторная поддержка и послеоперационные исходы: российское национальное эпидемиологическое исследование «РуВент-А»: протокол исследования

Андрей Игоревич Ярошецкий; Н. В. Трембач; С. Г. Парванян; В. В. Кузьков; В. А. Мазурок; А. И. Грицан; А. В. Власенко; А. А. Еременко; Р. Д. Комнов; И. Б. Заболотских

doi:10.21320/1818-474X-2025-2-47-57

No. 2 (2025), STUDY PROTOCOL

No. 2 (2025)

STUDY PROTOCOL

Perioperative respiratory support and postoperative outcomes: russian national epidemiological study RuVent-A: a study protocol

Published 30.04.2025

Andrey I. Yaroshetskiy

Sechenov First Moscow State Medical University, Moscow, Russia

https://orcid.org/0000-0002-1484-092X

N.V. Trembach

Kuban State Medical University, Krasnodar, Russia; Krasnodar Regional Hospital No 2, Krasnodar, Russia

https://orcid.org/0000-0001-7879-4793

S.G. Parvanyan

Nikiforov All-Russian Center for Emergency and Radiation Medicine, St. Petersburg, Russia

https://orcid.org/0000-0001-8141-0551

V.V. Kuzkov

Northern State Medical University, Arkhangelsk, Russia

https://orcid.org/0000-0002-8191-1185

V.A. Mazurok

Almazov National Medical Research Centre, St. Petersburg, Russia

https://orcid.org/0000-0003-3917-0771

A.I. Gritsan

Voyno-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russia; Krasnoyarsk Regional Center for Medical Education, Krasnoyarsk, Russia

https://orcid.org/0000-0002-0500-2887

A.V. Vlasenko

Russian Medical Academy of Continuing Professional Education, Moscow, Russia

https://orcid.org/0000-0003-4535-2563

A.A. Eremenko

Petrovsky National Research Centre of Surgery, Moscow, Russia

https://orcid.org/0000-0001-5809-8563

R.D. Komnov

Petrovsky National Research Centre of Surgery, Moscow, Russia

https://orcid.org/0000-0002-1128-362X

I.B. Zabolotskikh

Kuban State Medical University, Krasnodar, Russia; Krasnodar Regional Hospital No 2, Krasnodar, Russia; Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia

https://orcid.org/0000-0002-3623-2546

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Keywords

postoperative pulmonary complications
surgery
respiratory support
perioperative period

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Yaroshetskiy A.I., Trembach N.V., Parvanyan S.G., Kuzkov V.V., Mazurok V.A., Gritsan A.I., Vlasenko A.V., Eremenko A.A., Komnov R.D., Zabolotskikh I.B. Perioperative respiratory support and postoperative outcomes: russian national epidemiological study RuVent-A: a study protocol. Annals of Critical Care. 2025;(2):47–57. doi:10.21320/1818-474X-2025-2-47-57.

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INTRODUCTION: Annually, approximately 230 million patients undergo general anesthesia and mechanical ventilation, which is associated with a high incidence of postoperative pulmonary complications (PPC). Despite the proven efficacy of protective ventilation, the actual respiratory support strategies in Russian operating rooms remain insufficiently studied, underscoring the relevance of the RuVent-A study. MATERIALS AND METHODS: In the multicenter observational study RuVent-A, data will be collected using specialized electronic forms (Center Card and Patient Protocol) integrated into a secure web platform that ensures anonymization, regular backup, and quality control of the data. onditions: This is a multicenter observational study of patients undergoing surgical interventions under mechanical ventilation. Patients: The study includes all patients over 18 years of age undergoing surgical interventions under general anesthesia over a period of 5 working days. Interventions: The study records respiratory support parameters (tidal volume, PEEP, FiO₂, ventilation modes, etc.), the type of surgical intervention, comorbidities, and the subsequent occurrence of PPC, while no changes to clinical protocols are made. RESULTS: The developed study design has been registered in the ClinicalTrials.gov database, confirming its compliance with international standards and ensuring the transparency of the research. CONCLUSIONS: It is anticipated that the results of RuVent-A will help identify current respiratory support strategies, determine key risk factors for PPC, and formulate recommendations for optimizing perioperative ventilation in Russia, ultimately enhancing the quality of medical care and patient safety.

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References

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