Change of the temperature balance of the brain in various types of general anesthesia

A.V. Butrov, K.A. Salimova, B.J. Torosyan, G.R. Makhmutova, P.P. Davydov

Peoplesʼ Friendship University of Russia, Moscow

For correspondence: Salimova Kamila Azatovna — resident Peoplesʼ Friendship University of Russia, Moscow, Moscow; e-mail:

For citation: Butrov AV, Salimova KA, Torosyan BJ, Makhmutova GR, Davydov PP. Change of the temperature balance of the brain in various types of general anesthesia. Alexander Saltanov Intensive Care Herald. 2018;3:72–6.

DOI: 10.21320/1818-474X-2018-3-72-76

Under the influence of general anesthesia various functions of the body can change depending on the main and concomitant diseases, the type and volume of the surgical intervention. General anesthesia is traditionally associated with the loss of normal thermoregulatory mechanisms. The intracranial temperature of 32 patients were measured in this study. These patients were divided into 3 groups depending on the type of general anesthesia. The brain temperature of all patients were measured by recording the strength of the electromagnetic radiation from deep brain tissues and also, the axillary and tympanic temperatures were measured. According to the thermometry results of the brain, it was evident that when using Propofol, the temperature of the brain during anesthesia decreased by 1.21 ± 0.19 °C. During the maintenance of inhalational anesthesia the temperature of the brain decreased by 0.69 ± 0.15 °C. There was a decrease of brain temperature in all patients from all 3 groups and the temperature gradient of the brain/axillary region increased. Therefore, we concluded that the decrease in brain temperature occurs not only because of thermoregulatory center temperature decrease, but also because of reduced brain metabolism and/or cerebral blood flow. Propofol in a greater degree causes brain temperature decrease which may be important for the prevention or treatment of conditions that are accompanied by an increase in brain temperature or perfusion-metabolic balance disturbances (for example in neuroanesthesiology and in operations on the main cerebral vessels).

Keywords: brain temperature, temperature balance, microwave thermometry, propofol, sevoflurane, general anesthesia

Received: 02.04.2018


  1. Choi J.W., Kim D.K., Kim J.K., et al. A retrospective analysis on the relationship between intraoperative hypothermia and postoperative ileus after laparoscopic colorectal surgery.PLoS One. 2018; 13(1): e0190711.
  2. Rogers A.D., Saggaf M., Ziolkowski N. A quality improvement project incorporating preoperative warming to prevent perioperative hypothermia in major burns. Burns. 2018; 44(5): 1279–1286.
  3. Cohen B., Meilik B., Weiss-Meilik A., et al. Intraoperative factors associated with postoperative complications in body contouring surgery. J. Surg. Res. 2018; 221: 24–29.
  4. Trescher K., Gleiss A., Boxleitner M., et al. Short-term clinical outcomes for intermittent cold versus intermittent warm blood cardioplegia in 2200 adult cardiac surgery patients. J. Cardiovasc. Surg (Torino). 2017; 58(1): 105–112.
  5. Young C.C., Sladen R.N. Temperature monitoring. Int. Anestesiol. Clin. 1996; 34(3): 149–174.
  6. Маршак М.Е. Термоэлектрические методы исследования регионарного кровообращения в острых и хронических опытах. Современные методы исследования функций сердечно-сосудистой системы. М., 1962: 179–188. [Marshak M.E. Termoelektricheskiye metodi issledovaniya regionarnogo krovoobrasheniya v ostrich I khronicheskikh opitakh. Sovremennie metodi issledovaniya funkciy cerdechno-sosudistoy sistemi. (Thermoelectric methods of investigation regional blood circulation in acute and chronic experiments. Modern methods of studying the functions of the cardiovascular system.) Moscow, 1962: 179–188. (In Russ)]
  7. Гречин В.Б. Применение терморезисторов в стереотаксической нейрохирургии. Вопросы нейрохирургии. 1972; 1: 57–60. [Grechin V.B. Primeneniye termorezistrov v stereotoksicheskoy neyrokhirurgii. Voprosi neyrokhirurgii. 1972; 1: 57–60. (In Russ)]
  8. Mayers P.O., Sadowski M.I., Barrett A.H. Microwave thermography. Principles, methods and clinical applications. J. of Microwave Power. 1979; 14(2): 105–115.
  9. В.А. Березовский. Измерение температуры различных участков коры больших полушарий головного мозга собаки как показатель функционального состояния нервной ткани. Автореф. дис. … канд. мед. наук. Киев, 1962. [V.A. Berezovskiy. Izmereniye temperaturi razlichnikh uchastkov kori bolshikh polushariy golovnogo mozga sobaki kak pokazatel funkcionalnogo sostoyaniya nervnoy tkani. (Measurement of the temperature of various parts of cortex of cerebral hemispheres of the dogʼs brain as an indicator of the functional state of the nerve tissue.) [dissertation] Kiev, 1962. (In Russ)]
  10. Koutsoupidou M., Groumpas E., Karanasiou I.S., et al. The effect of using a dielectric matching medium in focused microwave radiometry: an anatomically detailed head model study. Med. Biol. Eng. Comput. 2018; 56(5): 809–816.
  11. Stauffer P.R., Snow B.W., Rodrigues D.B., et al. Non-Invasive Measurement of Brain Temperature with Microwave Radiometry: Demonstration in a Head Phantom and Clinical Case. Neuroradiol. J. 2014; 27(1): 3–12.
  12. Цейтлин А.М., Лубнин А.Ю. Применение пропофола в нейроанестезиологии [электронный документ]. URL: (Дата обращения: 18.08.2018.) [Ceytlin A.M., Lubnin A.U. Primeneniye propofola v neyroanesteziologii. (The use of propofol in neuroanesthesiology.) [Internet] URL: (In Russ)]