Clinical and Prognostic Aspects of Water-Electrolyte Homeostasis Disorders in the Acute Period of Ischemic Stroke

V.I. Ershov2, L.A. Aizhanova1, A.N. Chirkov1, A.M. Nazarov1,2, A.P. Gonchar-Zaikin2

1 Orenburg Regional Clinical Hospital, Orenburg

2 Orenburg State Medical University of the Ministry of Public Health of the Russian Federation, Orenburg

For correspondence: Vadim Ivanovich Ershov — doctor of Medical Sciences, Professor, Head of the Department of Anesthesiology and Reanimation of the Orenburg State Medical University, Director of the University Scientific Center of Neurology, Neuroreanimatology and Neurosurgery; e-mail: ervad2010@yandex.ru

For citation: Ershov VI, Aizhanova LA, Chirkov AN, Nazarov AM, Gonchar-Zaikin AP. Clinical and Prognostic Aspects of Water-Electrolyte Homeostasis Disorders in the Acute Period of Ischemic Stroke. Intensive Care Herald. 2017;4:53–57.


The aim. To reveal the influence of water-electrolyte disorders markers in the severe ischemic stroke acute period on the outcomes. Material and methods. The study included 150 patients with severe ischemic stroke of various pathogenetic subtypes. We studied the osmolarity and plasma sodium level (in the first day from the onset) influence on the prognosis of ischemic stroke. Results and discussion. The most common form of water-electrolyte disorders in patients with severe ischemic stroke is a hyperosmolar syndrome. Hypernatriemic hyperosmolar syndrome developed in patients at the onset of severe ischemic stroke is a predictor of an unfavorable outcome and is associated with higher lethality. The cardioembolic subtype of the ischemic stroke is associated with higher risk of death.

Keywords: ischemic stroke, pathogenic subtype, osmolarity

Received: 13.02.2017


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