Analgesic efficacy and safety of regional anesthesia methods in the perioperative period of surgical treatment of unstable spinal fractures: a randomized study
ISSN (print) 1726-9806     ISSN (online) 1818-474X
PDF_2024-1_124-134 (Russian)

Keywords

erector spinae plane block
ESP block
unstable vertebral fractures
epidural analgesia

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1.
Morunova A.Y., Ezhevskaya A.A. Analgesic efficacy and safety of regional anesthesia methods in the perioperative period of surgical treatment of unstable spinal fractures: a randomized study. Annals of Critical Care. 2024;(1):124-134. doi:10.21320/1818-474X-2024-1-124-134

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Abstract

INTRODUCTION: Perioperative anesthesia in spinal surgery is important areas of anesthesiology. Comparison of spine-straightening muscle block (Erector spinae plane block, ESP block) and epidural anesthesia (EA) during spinal surgery may access its effectiveness and safety. OBJECTIVE: To evaluate the efficacy and safety of a single and extended ESP block compared with epidural analgesia in the perioperative period of treatment of unstable vertebral fractures. MATERIALS AND METHODS: A prospective trial involved 110 patients. Three groups of patients were identified: group 1 (n = 35) — with bonuses P block; group 2 (n = 30) — with prolonged ESP block, group 3 (n = 45) — with prolonged epidural analgesia. Systemic hemodynamics, total opioid consumption, pain intensity, complications, the need for additional analgesia were evaluated. RESULTS: There were no differences in hemodynamics and opioid consumption in the intraoperative period. Six hours after surgery the groups with prolonged ESP block (group 2) and prolonged epidural analgesia (group 3) had lower pain indicators on the VAS scale than for group 1. The need for anesthesia (tramadol) for group 1 was significantly higher than for other groups, and amounted to 78 %. The need of opioid was 3 % for group 1, in other groups it was not required. PTR was present in a small percentage in each of the groups, but no statistical differences were found (p = 0.45). In the group with EA, there were 3 cases of urinary retention, 1 case of hip paresthesia. CONCLUSIONS: The use of ESP block allows to achieve effective and safe analgesia during spinal surgery for unstable vertebral fractures. Longer analgesia is provided by prolonged use of the ESP block than by its single use. When compared with prolonged EA, no significant differences were found in the effectiveness of analgesia, the consumption of opioids and the frequency of PTR.

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References

  1. Толкачев В.С., Бажанов С.П., Ульянов В.Ю. и др. Эпидемиология травм позвоночника и спинного мозга. Саратовский научно-медицинский журнал. 2018; 14(3): 592–5. [Tolkachev V.S., Bazhanov S.P., Ulyanov V.Yu., et al. The epidemiology of spine and spinal cord injuries (review). Saratov Journal of Medical Scientific Research. 2018; 14 (3): 592–5. (In Russ)]
  2. Рузиев Х.Х., Басков А.В., Басков В.А. и др. Лечение неосложненных компрессионных переломов позвоночника. Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко. 2019; 83(2): 66–70. DOI: 10.17116/neiro20198302166 [Ruziev Kh.Kh., Baskov A.V., Baskov V.A., et al. Treatment of uncomplicated vertebral compression fractures. Zhurnal Voprosy Neirokhirurgii Imeni N.N. Burdenko. 2019; 83(2): 66–70. DOI: 10.17116/neiro20198302166 (In Russ)]
  3. Исмаилова Ю.С., Алтаева А.Ж., Ахметов Ж.Б. и др. Патоморфогенетические аспекты влияния опиатных анальгетиков на организм человека (обзор). Вестник Казахского Национального медицинского университета. 2014; 2(2): 85–7. [Ismailova Yu.S., Altayeva A.Zh., Akhmetov Zh. B. et al. Pathomorphogenetic aspects of the effect of opiate analgesics on the human body (review). Bulletin of the Kazakh National Medical University. 2014; 2(2): 85–7 (In Russ)]
  4. Осипова Н.А., Петрова В.В. Типы боли и основные группы антиноцицептивных средств. Регионарная анестезия и лечение острой боли. 2013; 7(1): 38–43. [Osipova N. A., Petrova V. V. Types of pain and the main groups of antinociceptive drugs. Regional anesthesia and treatment of acute pain. 2013; 7(1): 38–43 (In Russ)]
  5. Голобородько В.Ю., Калинин А.А., Бывальцев В.А. Эффективность программы оптимизации нейроанестезиологической помощи при хирургическом лечении дегенеративных заболеваний поясничного отдела позвоночника у пациентов с факторами высокого риска. Анестезиология и реаниматология. 2021; 2: 74–89. DOI: 10.17116/anaesthesiology202102174 [Goloborodko V.Yu., Kalinin A.A., Byvaltsev V.A. Effectiveness of optimization program of neuroanesthesia in surgical treatment of degenerative lumbar spine diseases in patients with high risk factors. Russian Journal of Anesthesiology and Reanimatology. 2021; 2: 74–89. DOI: 10.17116/anaesthesiology202102174 (In Russ)]
  6. Forero M., Adhikari S.D., Lopez H. et al. A block in the plane of the spine erector: a new method of anesthesia for neuropathic chest pain. Restorative analgesic. 2016; 41(5): 621–7. DOI: 10.1097/AAP.0000000000000451.
  7. Морунова А.Ю., Ежевская А.А., Андрианова Т.О. и др. Эффективность блокады межфасциального пространства мышцы, выпрямляющей позвоночник (erector spinae plane block) при операциях поясничного спондилодеза. Регионарная анестезия и лечение острой боли. 2022; 16(2): 139–49. DOI: 10.17816/RA108416 [Morunova A.Yu., Yezhevskaya A.A., Andrianova T.O. et al. The effectiveness of blockade of the interfacial space of the muscle straightening the spine (the muscle straightening the spine of the block plane) during lumbar fusion operations. Regional anesthesia and treatment of acute pain. 2022; 16(2): 139–49. DOI: 10.17816/RA108416 (In Russ)].
  8. Xiao X., Zhu T., Wang L. et al. Efficacy of Postoperative Analgesia by Erector Spinal Plane Block after Lumbar Surgery: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Comput Math Methods Med. 2022: 3264142. DOI: 10.1155/2022/3264142.
  9. Овечкин А.М., Политов М.Е., Морозов Д.В. Неврологические осложнения регионарной анестезии. Регионарная анестезия и лечение острой боли. 2018;12(1): 6–14. DOI: 10.18821/1993-6508-2018-12-1-6-14 [Ovechkin A.M., Politov M.E., Morozov D.V. Neurological complications of regional anesthesia. Regional Anesthesia and Acute Pain Management. 2018; 12(1): 6–14. DOI: 10.18821/1993-6508-2018-12-1-6-14 (In Russ)]
  10. Раваль Н. Эпидуральная анальгезия: больше не золотой стандарт послеоперационного обезболивания? Регионарная анестезия и лечение острой боли.2012; 6(4): 29–44. [Raval N. Epidural analgesia: no longer the gold standard of postoperative analgesia? Regional anesthesia and treatment of acute pain. 2012; 6(4): 29–44. (In Russ)]
  11. Tsui B.C.H., Fonseca A., Munshey F. et al. The erector spinae plane (ESP) block: A pooled review of 242 cases. J Clin Anesth. 2019; 53: 29–34. DOI: 10.1016/j.jclinane.2018.09.036.
  12. Genc C., Kaya C., Bilgin S. et al. Pectoserratus plane block versus erector spinae plane block for postoperative opioid consumption and acute and chronic pain after breast cancer surgery: A randomized controlled trial. J Clin Anesth. 2022; 79: 110691. DOI: 10.1016/j.jclinane.2022.110691.
  13. Huang W., Wang W., Xie W. et al. Erector spinae plane block for postoperative analgesia in breast and thoracic surgery: A systematic review and meta-analysis. J Clin Anesth. 2020; 66: 109900. DOI: 10.1016/j.jclinane.2020.109900.
  14. Luo R., Tong X., Yan W. et al. Effects of erector spinae plane block on postoperative pain in children undergoing surgery: A systematic review and meta-analysis of randomized controlled trials. Paediatr Anaesth. 2021; 31(10): 1046–55. DOI: 10.1111/pan.14255.
  15. Лахин Р.Е., Шаповалов П.А., Щеголев А.В. и др. Эффективность использования erector spinae plane блокады при кардиохирургических операциях: систематический обзор и метаанализ. Анестезиология и реаниматология. 2022; 6: 29–43. DOI: 10.17116/anaesthesiology202206129 [Lakhin R.E., Shapovalov P.A., Shchegolev A.V., et al. Effectiveness of erector spinae plane blockade in cardiac surgery: a systematic review and meta-analysis. Russian Journal of Anaesthesiology and Reanimatology. 2022; 6: 29–43. DOI: 10.17116/anaesthesiology202206129 (In Russ)]
  16. Dultz L.A., Ma R., Dumas R.P., et al. Safety of Erector Spinae Plane Blocks in Patients With Chest Wall Trauma on Venous Thromboembolism Prophylaxis. J Surg Res. 2021; 263:124–9. DOI: 10.1016/j.jss.2021.01.020.
  17. Toscano A., Capuano P., Galata M. et al. Safety of Ultrasound-Guided Serratus Anterior and Erector Spinae Fascial Plane Blocks: A Retrospective Analysis in Patients Undergoing Cardiac Surgery While Receiving Anticoagulant and Antiplatelet Drugs. J Cardiothorac Vasc Anesth. 2022; 36(2): 483–8. DOI: 10.1053/j.jvca.2021.05.037.
  18. Ульрих Г.Э., Рязанова О.В., Заболотский Д.В. и др. Спинальная анестезия при операции кесарева сечения после хирургической коррекции деформации позвоночника многоопорной конструкцией. Анестезиология и реаниматология. 2023;(3):67–71. DOI: 10.17116/anaesthesiology202303167 [Ulrikh G.E., Ryazanova O.V., Zabolotskii D.V., et al. Spinal anesthesia during cesarean section in a patient with multi-support construction after previous correction of spinal deformity. Russian Journal of Anesthesiology and Reanimatology. 2023; 3: 67–71. DOI: 10.17116/anaesthesiology202303167 (In Russ)]
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