Аннотация
В статье отражены основные положения клинических рекомендаций Федерации анестезиологов и реаниматологов России по периоперационному ведению пациентов с артериальной гипертензией. Представлены классификация гипертензии, принципы стратификации риска возникновения в периоперационный период осложнений, связанных с имеющейся у пациента гипертензией. Описаны принципы клинико-инструментальной и лабораторной диагностики состояния таких пациентов. Приведены принципы и подходы к лечению неотложных и критических состояний, связанных с гипертензией. Даны алгоритм предоперационной оценки пациента и рекомендации по планированию оперативных вмешательств у пациентов с артериальной гипертензией. Подробно описаны принципы и алгоритмы предоперационной подготовки, включая антигипертензивную терапию, премедикацию, особенности выбора и проведения анестезии и ведение раннего послеоперационного периода. Вся информация, представленная в статье, основана на данных доказательной медицины, полученных отечественными и зарубежными исследователями.
Библиографические ссылки
- Abbott T.E.F., Pearse R.M., Archbold R.A., et al. Association between preoperative pulse pressure and perioperative myocardial injury: an international observational cohort study of patients undergoing non-cardiac surgery. Br J Anaesth. 2017; 119: 78e86.
- Ackland G.L., Abbott T.E.F., Pearse R.M., et al. Arterial pulse pressure and postoperative morbidity in high-risk surgical patients. Br J Anaesth. 2018; 120: 94e100.
- Ackland G.L., Brudney C.S., Cecconi M., et al. Perioperative Quality Initiative consensus statement on the physiology of arterial blood pressure control in perioperative medicine. Br J Anaesth. 2019; 122(5): 542–551. DOI: 10.1016/j.bja.2019.01.011
- Aronson S., Dyke C.M., Stierer K.A., et al. The ECLIPSE trials: compara-tive studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipinefor acute hypertension treatment in cardiac surgery patients. Anesth. Analg. 2008; 107(Suppl. 4.): 1110–1121.
- Bangalore S., Wetterslev J., Pranesh S., et al. Perioperative beta blockers in patients having non-cardiac surgery: a meta-analysis. Lancet. 2008; 372: 1962e76.
- Basali A., Mascha E.J., Kalfas I., Schubert A. Relation between perioperative hypertension and intracranial hemorrhage after craniotomy. Anesthesiology. 2000; 93: 48e54.
- Benetos A., Thomas F., Bean K.E., et al. Why cardiovascular mortality is higherin treated hypertensives versus subjects of the same age, in the general population. J. Hyper. 2003; 21(Suppl. 9): 1635–1640.
- Borghi C., Agabiti Rosei E., Bardin T., et al. Serum uric acid and the risk of cardiovascular and renal disease. J Hypertens. 2015; 33: 1729–1741; discussion 1741.
- Bouri S., Shun-Shin M.J., Cole G.D., et al. Metaanalysis of secure randomised controlled trials of betablockade to prevent perioperative death in non-cardiac surgery. Heart. 2014; 100: 456e64.
- Brook R.D., Rajagopalan S. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults. A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Journal of the American Society of Hypertension. 2018; Jan: 10–132.
- Casadei B., Abuzeid H. Is there a strong rationale for deferring elective surgery in patients with poorly controlled hypertension? J Hypertens. 2005; 23: 19–22.
- Chapman M.J., Ginsberg H.N., Amarenco P., et al. European Atherosclerosis Society Consensus Panel. Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management. Eur Heart J. 2011; 32: 1345–1361.
- Charlson M.E., MacKenzie C.R., Gold J.P., et al. Intraoperative blood pressure. What patterns identify patients at risk for postoperative complications? Ann Surg. 1990; 212: 567e80.
- Chatzizisis Y.S., Coskun A.U., Jonas M., et al. Role of endothelial shear stressin the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular, and vascular behavior. J. Am. Coll. Cardiol. 2007; 26(25): Suppl. 49: 2379–2393.
- Chobanian A.V. Hypertension in 2017 what is the right target? JAMA. 2017; 317: 579e80.
- Clark C.E., Taylor R.S., Shore A.C., et al. Association of a difference in systolic blood pressure between arms with vascular disease and mortality: a systematic review and metaanalysis. Lancet. 2012; 379: 905–914.
- Colan S.D., Lipshultz S.E., et al. Epidemiology and Cause-Specific Outcomeof Hypertrophic Cardiomyopathy in Children: Findings From the Pediatric Car-diomyopathy Registry. Circulation. 2007; 115: 773–781.
- Cordero A., Morillas P., Bertomeu-Gonzalez V., et al. Prevalence of Peripheral Arterial Disease in Patients with Acute Coronary SyndromeInvestigators. Clustering of target organ damage increases mortality after acute coronary syndromes in patients with arterial hypertension. J Hum Hypertens. 2011; 25: 600–607.
- Coriat P., Richer C., Douraki T., et al. Influence of chronic angiotensin-con-verting enzyme inhibition on anesthetic induction. Anesthesiology. 1994; 81(Suppl. 2): 299–307.
- Devereaux P.J., Yang H., Yusuf S., et al. Effects of extendedrelease metoprolol succinate in patients undergoing noncardiac surgery (POISE trial): a randomised controlled trial. Lancet. 2008; 371: 1839e47.
- Drenger B., Fontes M.L., Miao Y., et al. Patterns of use of perioperative angiotensin-converting enzyme inhibitors in coronary artery bypass graft surgery with cardiopulmonary bypass: effects on in-hospital morbidity and mortality. Circulation. 2012; 126: 261e9.
- Eagle K.A., Berger P.B., Calkins H., et al. ACC/AHA guideline update forperioperative cardiovascular evaluation for noncardiac surgery — executive sum-mary: a report of the American College of Cardiology. American Heart Association Task Force on Practice Guidelines (Committee to Update the 1996 Guidelineson Perioperative Cardiovascular Evaluation for Noncardiac Surgery). Am. Coll. Cardiol. 2002; 39: 542–553.
- Eaton M.P., Bailey P.L. Cardiovascular pharmacology of anesthetics. In: Cardiac Anesthesia: Principles and Clinical Practice. Estafanous F.G., Barash P.G., Reves J.G., eds. Lippincott Williams & Wilkins, 2001: 295–315.
- Fleisher L.A. Preoperative evaluation of the patient with hypertension. JAMA. 2002; 287(16): 2043–2046.
- Fleisher L.A., Barash P.G. Cardiac Anesthesia. 2001.
- Fleisher L.A., Fleischmann K.E., Auerbach A.D., et al. 2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery: a report of the American College of ardiology. American Heart Association Task Force on practice guidelines. J Am Coll Cardiol. 2014; 64(22): e77–137. DOI: 10.1016/j.jacc.2014.07.944
- Fontes M.L., Aronson S., Mathew J.P., et al. Pulse pressure and risk of adverse outcome in coronary bypass surgery. Anesth Analg. 2008; 107: 1122e9.
- Futier E., Lefrant J.Y., Guinot P.G., et al. Effect of individualized vs standard blood pressure management strategies on postoperative organ dysfunction among high-risk patients undergoing major surgery: a randomized clinical trial. JAMA. 2017; 318: 1346e57.
- Goldman L., Caldera D.L. Risk of general anesthesia and elective operationin the hypertensive patient. Anesthesiology. 1979; 50: 285–292.
- Grant I.S., Nimmo G.R., Nimmo S. Intercurrent disease and anaesthesia. Textbook of Anaesthesia. A.R. Aitkenhead, G. Smith, D.J. Rowbotham. Churchill Livingstone, 2007: 444–483.
- Guay J., Choi P., Suresh S., et al. Neuraxial blockade for the prevention of post-operative mortality and major morbidity: an overview of Cochrane systematic reviews. Cochrane Database Syst Rev. 2014; 1: CD010108.
- Hart G.R., Anderson R.J. Withdrawal syndromes and the cessation of antihypertensive therapy. Arch Intern Med 1981; 141: 1125e7.
- Howell S.J., Sear J.W., Foeх P. Hypertension, hypertensive heart disease and peri-operative cardiac risk. Br J Anaesth. 2004; 92: 570–583.
- Jackson C.E., Castagno D., Maggioni A.P., et al. Differing prognostic value of pulse pressure in patients with heart failure with reduced or preserved ejection fraction: results from the MAGGIC individual patient meta-analysis. Eur Heart J. 2015; 36: 1106e14.
- Jeger R.V., Probst C., Arsenic R., et al. Longterm prognostic value of the pre-operative 12-lead electrocardiogram before major noncardiac surgery in coronary artery disease. Am Heart J. 2006; 151: 508–513.
- Katz A.M. Cardiomyopathy of Overload — A Major Determinant of Prognosis in Congestive Heart Failure. N. Engl. J. Med. 1990; 322: 100–110.
- Kreepala C., Luangphiphat W., Villarroel A., et al. Effect of Magnesium on Glomerular Filtration Rate and Recovery of Hypertension in Women with Severe Preeclampsia. Nephron [Internet]. 2017; 138(1): 35–41.
- Kristensen S.D., Knuuti J., Saraste A., et al. Authors/Task Force Members. 2014ESC/ESA Guidelines on non-cardiac surgery: cardiovascular assessment and man-agement: The Joint Task Force on non-cardiac surgery: cardiovascular assessmentand management of the European Society of Cardiology (ESC) and the EuropeanSociety of Anaesthesiology (ESA). Eur. Heart. J. 2014; 14(35), Suppl. 35: 2383–2431.
- Levin M.A., Fischer G.W., Lin H.M., et al. Intraoperative arterial blood pressure lability is associated with improved 30 day survival. Br J Anaesth. 2015; 115: 716e26.
- Levy D., Garrison R.J., Savage D.D., et al. Prognostic implications of echocardiographically determined left ventricular mass in the FraminghamHeart Study. N Engl J Med. 1990; 322: 1561–1566.
- Lewington S. et al. Age-specific relevance of usual blood pressure to vascularmortality: A meta-analysis of individual data for one million adults in 61 prospec-tive studies. Lancet. 2002; 360: 1903–1913.
- Lipsitz L.A., Mukai S., Hamner J., Gagnon M., Babikian V. Dynamic regulation of middle cerebral artery blood flow velocity in aging and hypertension. Stroke. 2000; 31: 1897e903.
- Lohmeier T.E., Iliescu R. The baroreflex as a long-term controller of arterial pressure. Physiology (Bethesda) 2015; 30: 148e58.
- London M.J., Hur K., Schwartz G.G., Henderson W.G. Association of perioperative beta-blockade with mortality and cardiovascular morbidity following major noncardiac surgery. JAMA. 2013; 309: 1704e13.
- Lv Y.B., Gao X., Yin Z.X., et al. Revisiting the association of blood pressure with mortality in oldest old people in China: community based, longitudinal prospective study. BMJ. 2018; 361: k2158.
- Mancia G., Fagard R., Narkiewicz K., et al. Task Force Members. 2013 ESH/ESC Guidelines for the management of arterial hypertension: the Task Force forthe management of arterial hypertension of the European Society of Hyperten-sion (ESH) and of the European Society of Cardiology (ESC). J. Hypertens. 2013; Vol. 31(Suppl. 7): 1281–1357.
- Marik P.E., Varon J. Hypertensive crises: Challenges and management. Chest. 2007; 131: 1949–1962.
- Marwick T.H., Gillebert T.C., Aurigemma G., Chirinos J., Derumeaux G., Galderisi M., et al. Recommendations on the use of echocardiography in adult hypertension: a report from the European Association of Cardiovascular Imaging (EACVI) and the American Society of Echocardiography (ASE). Eur Heart J Cardiovasc Imaging. 2015; 16: 577–605.
- Mascha E.J., Yang D., Weiss S., Sessler D.I. Intraoperative mean arterial pressure variability and 30-day mortality in patients having noncardiac surgery. Anesthesiology. 2015; 123: 79e91.
- McEvoy M.D., Gupta R., Koepke E.J. et al. Perioperative Quality Initiative consensus statement on postoperative blood pressure, risk and outcomes for elective surgery. Br J Anaesth. 2019; 122(5): 575–586. DOI: 10.1016/j.bja.2019.01.019
- McLeod T. Postoperative management. In: Fundamentals of Anaesthesia. Pin-nock C.A., Lin T., Smith T. (eds.). Greenwich Medical Media Ltd., 2003: 60–80.
- Monk T.G., Bronsert M.R., Henderson W.G., et al. Association between intraoperative hypotension and hypertension and 30-day postoperative mortality in noncardiac surgery. Anesthesiology. 2015; 123: 307e19.
- Nishimori M., Low J.H.S., Zheng H., et al. Epidural pain relief versus systemic opioid-based pain relief for abdominal aortic surgery. Cochrane Database Syst Rev. 2012; 7: 7: CD005059.
- Ogoh S., Brothers R.M., Eubank W.L., Raven P.B. Autonomic neural control of the cerebral vasculature: acute hypotension. Stroke 2008; 39: 1979e87.
- Okin P.M., Devereux R.B., Jern S., et al. LIFE Study Investigators. Regression of electrocardiographic left ventricular hypertrophy during antihypertensive treatment and the prediction of major cardiovascular events. JAMA. 2004; 292: 2343–2349.
- Pagel P.S., Farber N.E., Warltier D.C. Cardiovascular Pharmacology. In: Miller’s Anaesthesia. R.D. Miller (еd.). Churchill Livingstone, Inc., 2000.
- Paix A.D. et al. Crisis management during anaesthesia: hypertension. QualSaf. Health Care. 2005; 14: 12.
- Pinnock C.A. Intra-operative management. In: Fundamentals of Anaesthesia. Pinnock C.A., Lin T., Smith T. (eds.). Greenwich Medical Media Ltd., 2003: 44–58.
- Poldermans D. et al. Guidelines for pre-operative cardiac risk assessmentand perioperative cardiac management in non-cardiac surgery. Eur. Heart J. 2009; 30: 2769–2812.
- Pöpping D.M., Elia N., Van Aken H.K., et al. Impact of epidural analgesia on mortality and morbidity after surgery: systematic review and meta-analysis of randomized controlled trials. Ann Surg. 2014; 259(6): 1056–1067. DOI: 10.1097/SLA.0000000000000237
- Prys-Roberts C., Meloche R., Foex P. Studies of anaesthesia in relation to hypertension. I. Cardiovascular responses of treated and untreated patients. Br J Anaesth. 1971; 43: 122e37.
- Reich D.L., Bennett-Guerrero E., Bodian C.A., et al. Intraoperative tachycardia and hypertension are independently associated with adverse outcome in noncardiac surgery of long duration. Anesth Analg. 2002; 95: 273e7.
- Reichek N., Devereux R.B. Left ventricular hypertrophy: relationship of anatomic, echocardiographic and electrocardiographic findings. Circulation. 1981; 63: 1391–1398.
- Richter Y., Edelman E.R. Cardiology Is Flow. Circulation. 2006; 113: 2679–2682.
- Rodgers A., Walker N., Schug S., et al. Reduction of post-operative mortality and morbidity with epidural or spinal anaesthesia: results from overview of randomised trials. BMJ. 2000; 321: 1493–1497.
- Roshanov P.S., Rochwerg B., Patel A., et al. Withholding versus continuing angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers before noncardiac surgery: an analysis of the vascular events in noncardiac surgery patients cohort evaluation prospective cohort. Anesthesiology. 2017; 126: 16e27.
- Salmasi V., Maheshwari K., Yang D., et al. Relationship between intraoperative hypotension, defined by either reduction from baseline or absolute thresholds, and acute kidney and myocardial injury after noncardiac surgery: a retrospective cohort analysis. Anesthesiology. 2017; 126: 47e65.
- Sanders R.D., Hughes F., Shaw A., et al. Perioperative Quality Initiative consensus statement on preoperative blood pressure, risk and outcomes for elective surgery. Br J Anaesth. 2019; 122(5): 552–562. DOI: 10.1016/j.bja.2019.01.018
- Sen S., Hinderliter A., et al. Aortic Arch Atheroma Progression and RecurrentVascular Events in Patients With Stroke or Transient Ischemic Attack. Circulation. 2007; 116: 928–935.
- Seshadri S., Wolf P.A., et al. Elevated Midlife Blood Pressure Increases StrokeRisk in Elderly Persons: The Framingham Study. Arch. Intern. Med. 2001; 161: 2343–2350.
- Sessler D.I., Bloomstone J.A., Aronson S., et al. Perioperative Quality Initiative consensus statement on intraoperative blood pressure, risk and outcomes for elective surgery. Br J Anaesth. 2019; 122(5): 563–574. DOI: 10.1016/j.bja.2019.01.013
- Sessler D.I., Meyhoff C.S., Zimmerman N.M., et al. Perioddependent associations between hypotension during and for four days after noncardiac surgery and a composite of myocardial infarction and death: a substudy of the POISE-2 Trial. Anesthesiology. 2018; 128: 317e27.
- Skeehan T., Jopling M. Monitoring the Cardiac Surgical Patient. In: A Practical Approach to Cardiac Anesthesia. Ed. F.A. Hensley, D.E. Martin, G.P. Gravlee. 3rd edition. Philadelphia, PA: Lippincott Williams & Wilkins, 2003: 99–140.
- Staessen J.A., Li Y., Thijs L., et al. Blood pressure reduction and cardiovascularprevention: an update including the 2003–2004 secondary prevention trials. Hypertens Res. 2005; 28(Suppl. 5): 385–407.
- Sun Y.P. et al. Comparative effects of ACE inhibitors and an angiotensin re-ceptor blocker on atherosclerosis and vascular function. J. Cardiovasc. Pharmacol. Ther. 2001; 6: 175–181.
- The fifth report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure. Arch. Intern. Med. 1993; 153: 154–183.
- Tsioufis C., Kokkinos P., Macmanus C., et al. Left ventricular hypertrophy as a determinant of renal outcome in patients with high cardiovascular risk. J Hypertens. 2010; 28: 2299–2308.
- Varas-Lorenzo C., Riera-Guardia N., Calingaert B., et al. Myocardial infarction and individual nonsteroidal antiinflammatory drugs meta-analysis of observational studies. Pharmacoepidemiol Drug Saf. 2013.
- Vasan R.S. Biomarkers of Cardiovascular Disease: Molecular Basis and Prac-tical Considerations. Circulation. 2006; 113: 2335–2362.
- Venkatesan S., Myles P.R., Manning H.J., et al. Cohort study of preoperative blood pressure and risk of 30-day mortality after elective non-cardiac surgery. Br J Anaesth. 2017; 119: 65e77.
- Verdecchia P., Angeli F. Natural History of Hypertension Subtypes. Circulation. 2005; 111: 1094–1096.
- Wallace A.W., Au S., Cason B.A. Association of the pattern of use of perioperative beta-blockade and postoperative mortality. Anesthesiology. 2010; 113: 794e805.
- Wheatley K., Ives N., Gray R., et al. Revascularization vs. medical therapy for renal-artery stenosis. N Engl J Med. 2009; 361: 1953–1962.
- Widlansky M.E., Gokce N., et al. The clinical implications of endothelial dysfunction. J.Am. Coll Cardiol. 2003; 42: 1149–1160.
- Wijeysundera D.N., Beattie W.S., Rao V., Karski J. Calcium antagonists reduce cardiovascular complications after cardiac surgery: a meta-analysis. J Am Coll Cardiol. 2003; 41: 1496e505.
- Wijeysundera D.N., Beattie W.S. Calcium channel blockers for reducing cardiac morbidity after noncardiac surgery: a meta-analysis. Anesth Analg. 2003; 97: 634e41.
- Wilkinson I.B., Franklin S.S., et al. Pressure Amplification Explains WhyPulse Pressure Is Unrelated to Risk in Young Subjects. Hypertension. 2001; 38: 1461–1466.
- Williams B., Mancia G., Spiering W., et al. ESC Scientific Document Group. 2018 ESC/ESH Guidelines for the management of arterial hypertension. Eur Heart J. 2018; 39(33): 3021–3104. DOI: 10.1093/eurheartj/ehy339
- Wirthlin D.J., Cambria R.P. Surgery-specific considerations in the cardiac patient undergoing noncardiac surgery. Prog Cardiovasc Dis. 1998; 40: 453–468.
- Wolman R.L., Nussmeier N.A., Aggarwal A., et al. Cerebral injury after cardiac surgery: identification of a group at extraordinary risk. Multicenter study of perioperative ischemia research group (McSPI) and the ischemia research education foundation (IREF) investigators. Stroke 1999; 30: 514e22.
- Артериальная гипертония у взрослых. Клинические рекомендации Минздрава. Российское медицинское общество по артериальной гипертонии. М., 2016. [Arterial’naya gipertoniya u vzroslyh. Klinicheskie rekomendacii Minzdrava. Rossijskoe medicinskoe obshchestvo po arterial’noj gipertonii. M., 2016. (In Russ)]
- Всероссийское научное общество кардиологов. Прогнозирование и профилактика кардиальных осложнений внесердечных хирургических вмешательств. Национальные рекомендации. М., 2011. Приложение 3 к журналу «Кардиоваскулярная терапия и профилактика». 2011; 10(Suppl. 6.). [Vserossijskoe nauchnoe obshchestvo kardiologov. Prognozirovanie i profilaktika kardial’nyh oslozhnenij vneserdechnyh hirurgicheskih vmeshatel’stv. Nacional’nye rekomendacii. M., 2011. Prilozhenie 3 k zhurnalu «Kardiovaskulyarnaya terapiya i profilaktika». 2011; 10(Suppl. 6.). (In Russ)]
- Кардиология. Национальное руководство: краткое издание. Под ред. акад. Е.В. Шляхто. 2-е изд., перераб. и доп. М.: ГЭОТАР-Медиа, 2018. [Kardiologiya. Nacional’noe rukovodstvo: kratkoe izdanie. Pod red. akad. E.V. SHlyahto. 2-e izd., pererab. i dop. M.: GEOTAR-Media, 2018. (In Russ)]
- Кардиология. Национальное руководство: краткое издание. Под ред. Ю.Н. Беленкова, Р.Г. Оганова. М.: ГЭОТАР-Медиа, 2012. [Kardiologiya. Nacional’noe rukovodstvo: kratkoe izdanie. Pod red. YU.N. Belenkova, R.G. Oganova. M.: GEOTAR-Media, 2012. (In Russ)]
- Кровообращение и анестезия. Под ред. К.М. Лебединского. СПб.: Человек, 2012. [Krovoobrashchenie i anesteziya. Pod red. K.M. Lebedinskogo. SPb.: CHelovek, 2012. (In Russ)]
- Лихванцев В.В. Ингаляционная индукция и поддержание анестезии. М.: МИА, 2003. [Lihvancev V.V. Ingalyacionnaya indukciya i podderzhanie anestezii. M.: MIA, 2003. (In Russ)]
- Меморандум экспертов Российского кардиологического общества по рекомендациям Европейского общества кардиологов / Европейского общества по артериальной гипертензии по лечению артериальной гипертензии 2018 г. Российский кардиологический журнал, 2018; 23(12): 131–142. [Memorandum ekspertov Rossijskogo kardiologicheskogo obshchestva po rekomendaciyam Evropejskogo obshchestva kardiologov / Evropejskogo obshchestva po arterial’noj gipertenzii po lecheniyu arterial’noj gipertenzii 2018 g. Rossijskij kardiologicheskij zhurnal, 2018; 23(12): 131–142. (In Russ)]
- Морган-мл. Дж.Э., Михаил М.С. Клиническая анестезиология. Пер. с англ. Кн. 1. М.; СПб.: БИНОМ, 2004. [Morgan-ml. Dzh.E., Mihail M.S. Klinicheskaya anesteziologiya. Per. s angl. Kn. 1. M.; SPb.: BINOM, 2004. (In Russ)]
- Периоперационное ведение больных с сопутствующими заболеваниями. Под ред. И.Б. Заболотских. М.: Практическая медицина, 2011. [Perioperacionnoe vedenie bol’nyh s soputstvuyushchimi zabolevaniyami. Pod red. I.B. Zabolotskih. M.: Prakticheskaya medicina, 2011. (In Russ)]
- Профилактика сердечно-сосудистых заболеваний в клинической практике. Рекомендации Европейского общества кардиологов (пересмотр 2012 г.). Российский кардиологический журнал. 2012; 4(96). Приложение 2. [Profilaktika serdechno-sosudistyh zabolevanij v klinicheskoj praktike. Rekomendacii Evropejskogo obshchestva kardiologov (peresmotr 2012 g.). Rossijskij kardiologicheskij zhurnal. 2012; 4(96). Prilozhenie 2. (In Russ)]
- Хороненко В.Э., Осипова Н. Анестезия в гериатрии и у пациентов с сопутствующими хроническими заболеваниями/ Анестезиология. Национальное руководство. Краткое издание. Гл. 19. Под ред. А.А. Бунятяна, В.М. Мизикова. М.: ГЭОТАР-Медиа, 2015: 515–545. [Horonenko V.E., Osipova N. Anesteziya v geriatrii i u pacientov s soputstvuyushchimi hronicheskimi zabolevaniyami/ Anesteziologiya. Nacional’noe rukovodstvo. Kratkoe izdanie. Gl. 19. Pod red. A.A. Bunyatyana, V.M. Mizikova. M.: GEOTAR-Media, 2015: 515–545. (In Russ)]
- Чазова И.Е., Ратова Л.Г. Изолированная систолическая артериальная гипертензия. Кардиология: национальное руководство. Под ред.Ю.Н. Беленкова, Р.Г. Оганова. М.: ГЭОТАР-Медиа, 2008. [Kardiologiya: nacional’noe rukovodstvo. Pod red.Yu.N. Belenkova, R.G. Oganova. M.: GEOTAR-Media, 2008. (In Russ)]