Full-text of the article is available for this locale: Russian.
Abstract
INTRODUCTION: In some cases, saliva production (sialorrhea — hypersalivation) can be so significant that it needs to be monitored and accounted for in the assessment and maintenance of the patient's water balance. OBJECTIVE: Description of a clinical case of sialorrhea, which had a clinically significant manifestation in the assessment and maintenance of water balance in a 2-month-old child in the intensive care unit (ICU). MATERIALS AND METHODS: Baby, 2 month old, was treated in the ICU with a diagnosis: perinatal organic hypoxic-ischemic lesion of the central nervous system of a newborn, congenital pathology of the brain, respiratory failure III stage, convulsions of the newborn, neonatal coma. In the complex of specific therapy, he received enteral feeding, correction of water and nutritional status. RESULTS: On the first day of detection of sialorrhea, the level of salivation of 2.81 ml/kg/hour (the norm is 1.3 ml/kg/hour) exceeded the physiological values by more than 2 times. The excess of normal values of salivation persisted for the next two days, as well as on the 9th day of its control, which required taking into account the amount of fluid lost with saliva in the calculation of its daily requirement. No specific measures were required in the treatment of the patient to eliminate sialorrhea; within 14 days from the moment the fact of sialorrhea was established, the level of salivation returned to normal values. CONCLUSIONS: In assessing the cumulative factors that cause fluid loss in ICU patients, especially infants, it is also necessary to take into account the presence and intensity of salivation, which can manifest as sialorrhea, when calculating the volume and administration of infusion drugs.
References
- Jacobs R., Wise R.D., Myatchin I., et al. Fluid Management, Intra-Abdominal Hypertension and the Abdominal Compartment Syndrome: A Narrative Review. Life (Basel). 2022;12(9):1390. DOI: 10.3390/life12091390
- Arrahmani I., Ingelse S.A., van Woensel J.B.M., et al. Current Practice of Fluid Maintenance and Replacement Therapy in Mechanically Ventilated Critically Ill Children: A European Survey. Front. Pediatr. 2022;10:828637. DOI: 10.3389/fped.2022.828637
- Лазарев В.В., Сулайманова Ж.Д., Цыпин Л.Е. и др. Выбор препарата инфузионной терапии в раннем послеоперационном периоде у детей. Общая реаниматология. 2020;16(5):30–6. DOI: 10.15360/1813-9779-2020-5-30-36 [Lazarev V.V., Sulaymanova Zh.D., Tsypin L.E., et al. The choice of infusion therapy drug in the early postoperative period in children. General Reanimatology. 2020;16(5):30–6. DOI: 10.15360/1813-9779-2020-5-30-36 (In Russ)]
- Лазарев В.В., Сулайманова Ж.Д., Цыпин Л.Е. и др. Препарат стартовой инфузионной терапии в раннем послеоперационном периоде у детей: 0,9% раствор натрия хлорида или сбалансированный полиионный раствор. Анестезиология и реаниматология. 2020;3:51–6. DOI: 10.17116/anaesthesiology202003151 [Lazarev V.V., Sulaimanova Zh.D., Tsypin L.E., et al. The drug of initial infusion therapy in the early postoperative period in children: 0.9% sodium chloride solution or a balanced polyionic solution. Anesthesiology and Reanimatology. 2020;3:51–6. DOI: 10.17116/anaesthesiology202003151 (In Russ)]
- Сулайманова Ж.Д., Лазарев В.В., Цыпин Л.Е. и др. Препарат стартовой инфузионной терапии в раннем послеоперационном периоде у детей: сукцинатсодержащий или малатсодержащий раствор. Вестник интенсивной терапии им. А.И. Салтанова. 2020;(3):129–36. DOI: 10.21320/1818-474X-2020-3-129-136 [Sulaimanova Z.D., Lazarev V.V., Tsypin L.E., et al. The fluids as starting infusion therapy in the early postoperative period in children: solution with succinate or malate. A prospective, randomized study. Annals of Critical Care. 2020;(3):129–36. DOI: 10.21320/1818-474X-2020-3-129-136 (In Russ)]
- Brossier D.W., Tume L.N., Briant A.R., et al. ESPNIC clinical practice guidelines: intravenous maintenance fluid therapy in acute and critically ill children—a systematic review and meta-analysis. Intensive Care Med. 2022;48(12): 1691–708. DOI: 10.1007/s00134-022-06882-z
- Гордеев В.И., Александрович Ю.С. АВС инфузионной терапии и парентерального питания в педиатрии. Пособие для врачей. Изд. 2-е, перераб. и доп. СПб., 2006. 74 с. [Gordeev V.I., Aleksandrovich Yu.S. ABC infusion therapy and parenteral nutrition in pediatrics. A guide for doctors. 2nd ed., revised and enlarged. SPb., 2006. 74 p. (In Russ)]
- Freudenreich O. Drug-induced sialorrhea. Drugs Today (Barc). 2005;41(6):411–8. DOI: 10.1358/dot.2005.41.6.893628
- Speyer R., Cordier R., Kim J.H., et al. Prevalence of drooling, swallowing, and feeding problems in cerebral palsy across the lifespan: a systematic review and meta-analyses. Dev Med Child Neurol. 2019;61(11):1249–58. DOI: 10.1111/dmcn.14316
- Leung A.K., Kao C.P. Drooling in children. Paediatr Child Health. 1999;4(6):406–11. DOI: 10.1093/pch/4.6.406
- Sforza E., Onesimo R., Leoni C., et al. Drooling outcome measures in paediatric disability: a systematic review. Eur J Pediatr. 2022;181:2575–92. DOI: 10.1007/s00431-022-04460-5
- Franco J.B., Cacita N., Freua K.A., et al. Treatment of drooling with scopolamine in pediatric ICU: A case series report. Spec Care Dentist. 2018;38(6):362–6. DOI: 10.1111/scd.12326
- Куренков А.Л., Кузенкова Л.М., Черников В.В. и др. Применение Incobotulinumtoxin A для лечения сиалореи у пациентов с детским церебральным параличом. Неврология, нейропсихиатрия, психосоматика. 2021;13(4):52–9. [Kurenkov A.L., Kuzenkova L.M., Chernikov V.V., et al. The use of Incobotulinumtoxin A for the treatment of sialorrhea in patients with cerebral palsy. Neurology, neuropsychiatry, psychosomatics. 2021;13(4):52–9. (In Russ)]

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