Comparison of REMS, NEWS, qSOFA scales and SIRS criteria in sepsis prediction for patients with confirmed SARS-CoV-2 infection: retrospective observational study
Issue 1 (2021) , INTENSIVE CARE IN COVID-19
Issue 1 (2021)
INTENSIVE CARE IN COVID-19

Comparison of REMS, NEWS, qSOFA scales and SIRS criteria in sepsis prediction for patients with confirmed SARS-CoV-2 infection: retrospective observational study

https://doi.org/10.21320/1818-474X-2021-1-48-56
Published 05.03.2021
Konstantin D. Zybin
Kuban State Medical University, Krasnodar, Russia; Regional Clinical Hospital # 2, Krasnodar, Russia
https://orcid.org/0000-0003-3571-986X
А.А. Noskov
Kuban State Medical University, Krasnodar, Russia; Regional Clinical Hospital # 2, Krasnodar, Russia
https://orcid.org/0000-0002-0662-9358
T.S. Musaeva
Kuban State Medical University, Krasnodar, Russia; Regional Clinical Hospital # 2, Krasnodar, Russia
https://orcid.org/0000-0001-9285-852X
М.P. Kuznetsova
Kuban State Medical University, Krasnodar, Russia
S.I. Goncharenko
Regional Clinical Hospital # 2, Krasnodar, Russia
https://orcid.org/0000-0002-7917-6396
O.V. Vysotsky
Regional Clinical Hospital # 2, Krasnodar, Russia
https://orcid.org/0000-0002-4152-8595
P.I. Danilyuk
Regional Clinical Hospital # 2, Krasnodar, Russia
https://orcid.org/0000-0002-9850-5685
E.S. Petrushenko
Regional Clinical Hospital # 2, Krasnodar, Russia
https://orcid.org/0000-0001-8943-5366
M.I. Veselenko
Regional Clinical Hospital # 2, Krasnodar, Russia
https://orcid.org/0000-0003-4988-4874
A.A. Potapova
Regional Clinical Hospital # 2, Krasnodar, Russia
https://orcid.org/0000-0002-9336-027X
S.V. Sinkov
Kuban State Medical University, Krasnodar, Russia; Regional Clinical Hospital # 2, Krasnodar, Russia
https://orcid.org/0000-0003-4483-4077
V.M. Durleshter
Kuban State Medical University, Krasnodar, Russia; Regional Clinical Hospital # 2, Krasnodar, Russia
https://orcid.org/0000-0002-7420-0553
#2021-1
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Keywords

REMS
NEWS
qSOFA
SIRS
prediction scales
sepsis
outcome
COVID-19

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Zybin K.D., Noskov А.А., Musaeva T.S., Kuznetsova М.P., Goncharenko S.I., Vysotsky O.V., Danilyuk P.I., Petrushenko E.S., Veselenko M.I., Potapova A.A., Sinkov S.V., Durleshter V.M. Comparison of REMS, NEWS, qSOFA scales and SIRS criteria in sepsis prediction for patients with confirmed SARS-CoV-2 infection: retrospective observational study. Annals of Critical Care. 2021;(1):48–56. doi:10.21320/1818-474X-2021-1-48-56.
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Abstract

Introduction. Novel coronavirus disease is often accompanied by sepsis. This leads us to search of sepsis prediction tools.

Objectives. Comparison of REMS, NEWS, qSOFA scales and SIRS criteria in sepsis prediction for patients with confirmed SARS-CoV-2 infection.

Materials and methods. 167 medical cards retrospective analysis of patients with confirmed SARS-CoV-2 infection on admission to ICU.

Results. In sepsis prediction only NEWS (0,819 [95% CI 0.738–0,884]) showed resolution high enough to serve as supplemental clinical information. REMS (0.798 [95% CI 0.715–0.866]), qSOFA (0.716 [95% CI 0.626–0.795]) and SIRS criteria (0.710 [95% CI 0.620–0.790]) showed insufficient resolution in sepsis prediction for patients with SARS-CoV-2. NEWS in pairwise comparison showed significantly better resolution than qSOFA (p = 0.002) and SIRS criteria (p = 0.013). All scales showed good calibration.

Conclusions. Only NEWS scale showed good resolution and calibration and can be used as supplemental clinical information in sepsis prediction for patients with SARS-CoV-2 infection.

https://doi.org/10.21320/1818-474X-2021-1-48-56
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