Abstract
The aim of the study was to assess the effect of the composition of the inhaled gas mixture on the recorded indicators of inspiratory respiratory volume in ventilator with controlled volume, and inspiratory pressure in the Airways, in ventilator with controlled pressure. To carry out the ventilation with a mixture of helium and oxygen, the Hamilton G5 (Hamilton Medical, Switzerland) ventilator was used with a unit that provides the possibility of supplying this type of mixture. To simulate the lungs, we used TestChest Respiratory Flight Simulator (Organis GmbH, Switzerland) with settings reflecting the patientʼs respiratory system, both in normal and in pathological conditions. According to the results of the study, the composition of the inhaled gas mixture during lung ventilation with controlled volume does not affect the recorded inspiratory respiratory volume on the models of normal and pathological lungs. However, during artificial ventilation of lungs with a mixture of helium and oxygen with controlled pressure, statistically significant differences in the recorded inspiratory pressure in the Airways on the model of lungs were revealed in comparison with the mechanical ventilation oxygen-air mixture.References
- Красновский А.Л., Григорьев С.П., Алехин А.И., Потапов В.Н. Применение подогреваемой кислородно-гелиевой смеси вкомплексном лечении пациентов с внебольничной пневмонией. Клиническая медицина. 2013; 5: 38–41. [Krasnovsky A.L., Grigoriev S.P., Alekhin A.I., Potapov V.N. Application of heated oxygen-helium mixture for combined treatment of community-acquired pneumonia. Klinicheskaya medicina. 2013; 5: 38–41. (In Russ)].
- Fink J. Opportunities and risks of using heliox in your clinical practice. Respiratory care. 2006; 6: 651–660.
- Tassaux D., Jolliet P., Thouret J., et al. Calibration of seven ICU ventilators for mechanical ventilation with helium-oxygen mixtures. Am. J. Respir. Crit. Care Med. 1999; 1: 22–32.
- Brown M., Willms D. A Laboratory Evaluation of 2 Mechanical Ventilators in the Presence of Helium-Oxygen Mixtures. Respir. Care. 2005; 3: 354–360.
- McArthur C, Adams A., Suzuki S. Effects of helium/oxygen mixtures on delivered and expired tidal volume during mechanical ventilation. Am. J. Respir. Crit. Care Med. 1996; 1: 370.
- Jaber S., Fodil R., Carlucci A., et al. Noninvasive ventilation with helium-oxygen in acute exacerbations of chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 2000; 161: 1191–1200.
- Oppenheim-Eden A., Cohen Y., Weissman C., Pizov R. The effect of helium on ventilator performance: study of five ventilators and a bedside Pitot tube spirometer. Chest. 2001; 2: 582–588.
- Venkataraman S. Heliox during mechanical ventilation. Respir. Care. 2006; 6: 632–639.
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Copyright (c) 2018 ANNALS OF CRITICAL CARE