The influence of the composition of inhaled gas mixture in the inspiratory tidal volume and airway pressure during mechanical ventilation with controlled volume and pressure (experimental study)
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PDF_2018-2_61-68 (Русский)

Keywords

mixture of helium and oxygen
oxygen-air mixture
mechanical ventilation of the lungs
the model of the lungs

How to Cite

Grachev I.N., Shchegolev A.V. The influence of the composition of inhaled gas mixture in the inspiratory tidal volume and airway pressure during mechanical ventilation with controlled volume and pressure (experimental study). Annals of Critical Care. 2018;(2):61–68. doi:10.21320/1818-474X-2018-2-61-68.

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Abstract

The aim of the study was to assess the effect of the composition of the inhaled gas mixture on the recorded indicators of inspiratory respiratory volume in ventilator with controlled volume, and inspiratory pressure in the Airways, in ventilator with controlled pressure. To carry out the ventilation with a mixture of helium and oxygen, the Hamilton G5 (Hamilton Medical, Switzerland) ventilator was used with a unit that provides the possibility of supplying this type of mixture. To simulate the lungs, we used TestChest Respiratory Flight Simulator (Organis GmbH, Switzerland) with settings reflecting the patientʼs respiratory system, both in normal and in pathological conditions. According to the results of the study, the composition of the inhaled gas mixture during lung ventilation with controlled volume does not affect the recorded inspiratory respiratory volume on the models of normal and pathological lungs. However, during artificial ventilation of lungs with a mixture of helium and oxygen with controlled pressure, statistically significant differences in the recorded inspiratory pressure in the Airways on the model of lungs were revealed in comparison with the mechanical ventilation oxygen-air mixture.
https://doi.org/10.21320/1818-474X-2018-2-61-68
PDF_2018-2_61-68 (Русский)

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