ISSN (print) 1726-9806     ISSN (online) 1818-474X
No. 4 (2023), CLINICAL GUIDELINES
No. 4 (2023)
CLINICAL GUIDELINES

Septic shock in adults: guidelines of the All-Russian public organization “Federation of Anesthesiologists and Reanimatologists”

Published 30.10.2023
M.Yu. Kirov
Northern State Medical University, Arkhangelsk, Russia
https://orcid.org/0000-0002-4375-3374
V.V. Kuzkov
Northern State Medical University, Arkhangelsk, Russia
https://orcid.org/0000-0002-8191-1185
D.N. Protsenko
Pirogov Russian National Research Medical University (RNRMU), Moscow, Russia; Moscow’s Multidisciplinary Clinical Center “Kommunarka”, Moscow, Russia
https://orcid.org/0000-0002-5166-3280
A.V. Shchegolev
Military Medical Academy, St. Petersburg, Russia
https://orcid.org/0000-0001-6431-439X
M.A. Babaev
Petrovsky National Research Centre of Surgery, Moscow, Russia
https://orcid.org/0000-0002-4288-3791
B.Z. Belotserkovskiy
Pirogov Russian National Research Medical University (RNRMU), Moscow, Russia; Moscow’s Multidisciplinary Clinical Center “Kommunarka”, Moscow, Russia
https://orcid.org/0000-0002-5758-5703
A.O. Bykov
Pirogov Russian National Research Medical University (RNRMU), Moscow, Russia; Moscow’s Multidisciplinary Clinical Center “Kommunarka”, Moscow, Rus
https://orcid.org/0000-0001-5244-7769
A.I. Gritsan
Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russia; Krasnoyarsk regional center of medical education, Krasnoyarsk, Russia
https://orcid.org/0000-0002-0500-2887
V.V. Kulabukhov
N.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow, Russia
https://orcid.org/0000-0003-1769-7038
A.V. Kulikov
Ural State Medical University, Yekaterinburg, Russia
https://orcid.org/0000-0002-7768-4514
V.L. Kupreichik
Moscow’s Multidisciplinary Clinical Center “Kommunarka”, Moscow, Russia
https://orcid.org/0000-0002-6966-576X
R.E. Lakhin
Military Medical Academy, St. Petersburg, Russia; Saratov State Medical University named after V.I. Razumovsky, Saratov, Russia
https://orcid.org/0000-0001-6819-9691
K.M. Lebedinskii
North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russia; Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
https://orcid.org/0000-0002-5752-4812
S.I. Rey
N.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow, Russia; Research Institute for Healthcare Development and Medical Management of Moscow Healthcare Department, Moscow, Russia
https://orcid.org/0000-0001-7802-2283
V.A. Rudnov
Ural State Medical University, Yekaterinburg, Russia
https://orcid.org/0000-0003-0830-786X
Alexey A. Smetkin
Northern State Medical University, Arkhangelsk, Russia
https://orcid.org/0000-0003-4133-4173
M.V. Surkov
Military Medical Academy, St. Petersburg, Russia
https://orcid.org/0000-0002-2274-5578
E.M. Shifman
Moscow Regional Research and Clinical Institute, Moscow, Russia
https://orcid.org/0000-0002-6113-8498
S.A. Shlyapnikov
St. Petersburg Research Institute of Emergency Medicine named after I.I. Dzhanelidze, St. Petersburg, Russia
https://orcid.org/0000-0002-6182-8333
M.B. Yarustovsky
A.N. Bakulev National Medical Research Сеnter for Cardiovascular Surgery of the Russian Ministry of Health, Moscow, Russia
https://orcid.org/0000-0002-1849-4745
I.B. Zabolotskikh
Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia; Kuban State Medical University, Krasnodar, Russia; Regional Clinical Hospital No 2, Krasnodar, Russia
https://orcid.org/0000-0002-3623-2546
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Keywords

septic shock
intensive care
clinical guidelines

How to Cite

1.
Kirov M.Y., Kuzkov V.V., Protsenko D.N., Shchegolev A.V., Babaev M.A., Belotserkovskiy B.Z., Bykov A.O., Gritsan A.I., Kulabukhov V.V., Kulikov A.V., Kupreichik V.L., Lakhin R.E., Lebedinskii K.M., Rey S.I., Rudnov V.A., Smetkin A.A., Surkov M.V., Shifman E.M., Shlyapnikov S.A., Yarustovsky M.B., Zabolotskikh I.B. Septic shock in adults: guidelines of the All-Russian public organization “Federation of Anesthesiologists and Reanimatologists.” Annals of Critical Care. 2023;(4):7-42. doi:10.21320/1818-474X-2023-4-7-42
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Abstract

The paper represents the clinical guidelines for septic shock in adults, approved by the All-Russian public organization “Federation of anesthesiologists and reanimatologists” in 2023. Septic shock is a widespread condition with a high mortality rate. The recommendations cover the issues of etiology, pathogenesis, clinical signs and symptoms, methods of laboratory and instrumental diagnosis of septic shock. The clinical guidelines present initial therapy for septic shock, including approaches to vasopressor and inotropic therapy, recommendations for choosing antibacterial drugs, fluid and adjuvant therapy. The issues of surgical treatment of the infection are discussed. The article contains the criteria for the quality of medical care for the adult patients with septic shock and algorithms for the decision making in the diagnosis and intensive care of patients with septic shock.

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